(Q34152011)

31 July 2017

title

Comments on the history and importance of aromatic and heterocyclic amines in public health (English)

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31 July 2017

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John H Weisburger

1

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31 July 2017

language of work or name

English

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publication date

1 September 2002

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31 July 2017

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31 July 2017

volume

506-507

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31 July 2017

page(s)

9-20

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Quantitative analysis of hemoglobin-xenobiotic adducts

31 July 2017

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The metabolism of xenobiotics to reactive electrophiles in chemical carcinogenesis and mutagenesis: a collaboration with Elizabeth Cavert Miller and our associates.

7 January 2021

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Aromatic amines as carcinogens in industry

7 January 2021

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Effect of dietary wheat bran and dehydrated citrus fiber on 3,2′-dimethyl-4-aminobiphenyl-induced intestinal carcinogenesis in F344 rats

7 January 2021

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Evaluation of two suggested methods of deactivating organic carcinogens by molecular modification

7 January 2021

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New Carcinogenic Naphthalene and Biphenyl Derivatives

7 January 2021

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Comparative carcinogenicity of o-toluidine hydrochloride and o-nitrosotoluene in F-344 rats

7 January 2021

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Estimation of N-hydroxy-o-toluidine, a urinary metabolite of o-toluidine and o-nitrosotoluene, by high performance liquid chromatography with electrochemical detection.

7 January 2021

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Chemistry, carcinogenicity, and metabolism of 2-fluorenamine and related compounds

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Reactivity in vivo of the Carcinogen N -Hydroxy-2-acetylaminofluorene: Increase by Sulfate Ion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Prostaglandin H synthase and xenobiotic oxidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Carcinogen substrate specificity of human COX-1 and COX-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Effects of green and black tea on hepatic xenobiotic metabolizing systems in the male F344 rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Inhibition of carcinogenesis by tea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mechanistic basis for nonlinearities and thresholds in rat liver carcinogenesis by the DNA-reactive carcinogens 2-acetylaminofluorene and diethylnitrosamine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mechanisms of chemical carcinogenesis and application to human cancer risk assessment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Nutrition and dietary carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mutagenicities of smoke condensates and the charred surface of fish and meat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Dietary fat and risk of chronic disease: mechanistic insights from experimental studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Meat consumption, cigarette smoking, and genetic susceptibility in the etiology of colorectal cancer: results from a Dutch prospective study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Formation of mutagens in cooked foods. I. Beef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Formation of mutagens in cooked foods. III. Isolation of a potent mutagen from beef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Minimization of heterocyclic amines and thermal inactivation of Escherichia coli in fried ground beef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Experimental and simulation studies of heat flow and heterocyclic amine mutagen/carcinogen formation in pan-fried meat patties.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Formation of a new mutagenic DiMeIQx compound in a model system by heating creatinine, alanine and fructose

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Cooking procedures and food mutagens: a literature review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mutagen formation in a model beef supernatant fraction. IV. Properties of the system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Extended quantitative structure-activity relationships for 80 aromatic and heterocyclic amines: structural, electronic, and hydropathic factors affecting mutagenic potency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Carcinogenicity in mice of a mutagenic compound, 2-amino-3-methylimidazo[4,5-f]quinoline, from broiled sardine, cooked beef and beef extract.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Studies on mammary carcinogenesis induced by a heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in mice and rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mammary gland carcinogenesis by food-derived heterocyclic amines: metabolism and additional factors influencing carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Health risks of heterocyclic amines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Carcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline in Nonhuman Primates: Induction of Tumors in Three Macaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Dietary heterocyclic amines and cancer of the colon, rectum, bladder, and kidney: a population-based study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Effect of cooking temperature on the formation of heterocyclic amines in fried meat products and pan residues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Meat consumption and colorectal cancer risk: dose-response meta-analysis of epidemiological studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/3. Animal studies suggesting involvement of mutagen/carcinogen exposure in atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non-Hispanic white California Seventh-day Adventists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Convergence of plant-rich and plant-only diets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Cooked-food mutagens: current knowledge of formation and biological significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Heterocyclic amines formed by cooking food: comparison of bioassay results with other chemicals in the Carcinogenic Potency Database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Biological significance of trace levels of mutagenic heterocyclic aromatic amines in human diet: a critical review.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Effect of microwave pretreatment on heterocyclic aromatic amine mutagens/carcinogens in fried beef patties.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Inhibitory effect of carbohydrates on the formation of mutagens in fried beef patties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Prevention of the formation of mutagenic and/or carcinogenic heterocyclic amines by food factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Formation of mutagens in cooked foods. V. The mutagen reducing effect of soy protein concentrates and antioxidants during frying of beef.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Tea polyphenols inhibit the formation of mutagens during the cooking of meat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

L-tryptophan inhibits formation of mutagens during cooking of meat and in laboratory models.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Metabolism of food-derived heterocyclic amines in nonhuman primates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mutagenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in the new gpt delta transgenic mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutation in the cecum and colon of big blue rats by conjugated linoleic acid and 1,2-dithiole-3-thione

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Transgenic mouse models in carcinogenesis research and testing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Early detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Genetic analysis of the susceptibility in rats to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine, PhIP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Heterocyclic aromatic amines induce DNA strand breaks and cell transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Cell transformation in vitro by food-derived heterocyclic amines Trp-P-1, Trp-P-2 and N(2)-OH-PhIP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Characterization of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the colon of gpt delta transgenic mouse: novel G:C deletions beside runs of identical bases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

DNA adduct levels of 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in tissues of cynomolgus monkeys after single or multiple dosing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Genomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Frequent c-Ha-ras gene mutations in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2'-dimethyl-4-aminobiphenyl (DMAB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Dose-dependent induction of aberrant crypt foci in the colons but no neoplastic lesions in the livers of heterozygous p53-deficient mice treated with low dose 2-amino-3-methylimidazo [4,5-f]quinoline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

32P-postlabeling methods for DNA adduct detection: overview and critical evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Inhibitory effect of green and black tea on tumor growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Antimutagenic and anticarcinogenic activity of tea polyphenols.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Search for compounds that inhibit the genotoxic and carcinogenic effects of heterocyclic aromatic amines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Antimutagenesis and anticarcinogenesis, from the past to the future

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Suppression of genotoxicity of carcinogens by (−)-epigallocatechin gallate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

7 January 2021

Tea and prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Urinary excretion of N-OH-2-amino-3-methylimidazo[4,5-f]quinoline-N-glucuronide in F344 rats is enhanced by green tea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Suppressing effect of Lactobacillus casei administration on the urinary mutagenicity arising from ingestion of fried ground beef in the human.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Effects of human intestinal flora on mutagenicity of and DNA adduct formation from food and environmental mutagens.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Metabolic activation of N-hydroxylated metabolites of carcinogenic and mutagenic arylamines and arylamides by esterification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Comparative biotransformation studies of MeIQx and PhIP in animal models and humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Monounsaturated and other types of fat, and the risk of breast cancer.

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Sprague-Dawley rats on high- and low-fat diets.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Role of fat and calcium in cancer causation by food mutagens, heterocyclic amines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Oxyradicals and DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Oxidative DNA damage: endogenous and chemically induced

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Involvement of free radicals in the formation of heterocyclic amines and prevention by antioxidants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Free radical generation from heterocyclic amines by cytochrome b5 reductase in the presence of NADH

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

Testing of some benzidine analogues for microsomal activation to bacterial mutagens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900147-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(02)00147-1

1 reference

31 July 2017

1 reference