(Q34153747)

31 July 2017

title

Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analogues (English)

1 reference

31 July 2017

Antitumor Agents. 280. Multidrug Resistance-Selective Desmosdumotin B Analogues (English)

1 reference

antineoplastic resistance

22 June 2024

main subject

multiple drug resistance

1 reference

based on heuristic

inferred from title

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

22 June 2024

5

Tzu-Hsuan Chen

1 reference

31 July 2017

9

Kenneth F Bastow

1 reference

31 July 2017

1

Kyoko Nakagawa-Goto

1 reference

31 July 2017

10

Kuo-Hsiung Lee

1 reference

31 July 2017

7

Hao Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

22 June 2024

author name string

Po-Cheng Chang

2

1 reference

31 July 2017

Chin-Yu Lai

3

1 reference

31 July 2017

Hsin-Yi Hung

4

1 reference

31 July 2017

Pei-Chi Wu

6

1 reference

31 July 2017

Alexander Sedykh

8

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 September 2010

1 reference

31 July 2017

23 September 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20735140

full work available at URL

22 June 2024

https://europepmc.org/articles/pmc2945214?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735140/?tool=EBI

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735140/pdf/?tool=EBI

22 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://europepmc.org/articles/PMC2945214

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://europepmc.org/articles/PMC2945214?pdf=render

22 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://doi.org/10.1021/jm100846r

22 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735140

https://pubs.acs.org/doi/pdf/10.1021/jm100846r

22 June 2024

1 reference

Journal of Medicinal Chemistry

22 June 2024

published in

1 reference

31 July 2017

volume

53

1 reference

31 July 2017

issue

18

1 reference

31 July 2017

page(s)

6699-6705

1 reference

Multidrug efflux pumps: drug binding--gates or cavity?

31 July 2017

cites work

1 reference

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Is resistance useless? Multidrug resistance and collateral sensitivity

5 July 2018

1 reference

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ABC efflux pump-based resistance to chemotherapy drugs.

5 July 2018

1 reference

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Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response.

5 July 2018

1 reference

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Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy.

5 July 2018

1 reference

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Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

An overview of cancer multidrug resistance: a still unsolved problem

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

ABC multidrug transporters: structure, function and role in chemoresistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Mechanism of multidrug recognition by MDR1/ABCB1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Flavonoid-drug interactions: effects of flavonoids on ABC transporters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Strategies for reversing drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

P-glycoprotein: from genomics to mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

New multidrug resistance reversal agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

The biochemistry and medical significance of the flavonoids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.

5 July 2018

1 reference

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P-glycoprotein as a drug target in the treatment of multidrug resistant cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

A multidrug resistance transporter from human MCF-7 breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

The biochemistry of P-glycoprotein-mediated multidrug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945214

Overcoming multidrug resistance in cancer: clinical studies of p-glycoprotein inhibitors

5 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20735140

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

8

58

5337

Allikmets R.

1998

1 reference

22 June 2024

9

59

8

Miyake K.

1999

1 reference

22 June 2024

Identifiers

DOI

10.1021/JM100846R

1 reference

31 July 2017

1 reference

31 July 2017

1 reference