(Q34155456)

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Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone

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8 February 2020

Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663888%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

protein folding

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Sunil Evan Saith

6

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8 February 2020

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Ming Liu

1

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8 February 2020

Qing-xin Hua

2

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8 February 2020

Shi-Quan Hu

3

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8 February 2020

Wenhua Jia

4

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8 February 2020

Yanwu Yang

5

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8 February 2020

Jonathan Whittaker

7

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8 February 2020

Peter Arvan

8

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8 February 2020

Michael A Weiss

9

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8 February 2020

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27 July 2010

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8 February 2020

Journal of Biological Chemistry

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8 February 2020

285

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8 February 2020

40

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8 February 2020

30989-31001

1 reference

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8 February 2020

An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Solution Structure of Proinsulin: CONNECTING DOMAIN FLEXIBILITY AND PROHORMONE PROCESSING

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Crystal Structure of a"Nonfoldable"Insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Proinsulin and the genetics of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Proinsulin maturation, misfolding, and proteotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Insulin gene mutations as a cause of permanent neonatal diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The experimental survey of protein-folding energy landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Characterization of the functional insulin binding epitopes of the full-length insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Role of the connecting peptide in insulin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Structural biology of insulin and IGF1 receptors: implications for drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Proteotoxicity in the endoplasmic reticulum: lessons from the Akita diabetic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

A cavity-forming mutation in insulin induces segmental unfolding of a surrounding α-helix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Linear extrapolation method of analyzing solvent denaturation curves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Application of circular dichroism to study RNA folding transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Protein misfolding, evolution and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

There's a right way and a wrong way: in vivo and in vitro folding, misfolding and subunit assembly of the P22 tailspike

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The fundamentals of protein folding: bringing together theory and experiment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The proprotein convertases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The role of assembly in insulin's biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

How evolution makes proteins fold quickly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

"New view" of protein folding reconciled with the old through multiple unfolding simulations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Theory of protein folding: the energy landscape perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The new era of biotech insulin analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

From Levinthal to pathways to funnels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Solution structure of an engineered insulin monomer at neutral pH

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Structure of a protein in a kinetic trap

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Synthesis of Insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Conformation of proinsulin. A comparison of insulin and proinsulin self-association at neutral pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The structure of 2Zn pig insulin crystals at 1.5 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Structure and activity dependence of recombinant human insulin-like growth factor II on disulfide bond pairing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The insulin A and B chains contain structural information for the formation of the native molecule. Studies with protein disulphide-isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Importance of the character and configuration of residues B24, B25, and B26 in insulin-receptor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Receptor binding redefined by a structural switch in a mutant human insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Insulin hexamers: new conformations and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Biosynthetic human proinsulin. Review of chemistry, in vitro and in vivo receptor binding, animal and human pharmacology studies, and clinical trial experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Altering the association properties of insulin by amino acid replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Structure of insulin in 4-zinc insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Proinsulin: a proposed three-dimensional structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Receptor-binding region of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

5 July 2018

Protein folding funnels: the nature of the transition state ensemble

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Oxidative refolding of insulin-like growth factor 1 yields two products of similar thermodynamic stability: a bifurcating protein-folding pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

A protein caught in a kinetic trap: structures and stabilities of insulin disulfide isomers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Mutational analysis of the absolutely conserved B8Gly: consequence on foldability and activity of insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

The different folding behavior of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Sequences of B-chain/domain 1-10/1-9 of insulin and insulin-like growth factor 1 determine their different folding behavior.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Hiking in the energy landscape in sequence space: a bumpy road to good folders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945590

28 October 2018

Measurement of the β-sheet-forming propensities of amino acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152645

21 January 2018

Evidence for a precursor in the biosynthesis of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors I and II are unable to form and maintain their native disulfides under in vivo redox conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinsulin and the biosynthesis of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of the A2 amino acid residue in the biological activity of insulin: [2-glycine-A]- and [2-alanine-A]insulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disulfide exchange folding of insulin-like growth factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proposed interaction model of the insulin molecule with its receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of the insulin-containing secretory granule core occurs within immature beta-granules

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steric requirements at position B12 for high biological activity in insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An overview of insulin evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and Proinsulin Conformation in Solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of des(tetrapeptide B(1-4)) and des(pentapeptide B(1-5)) human insulins. Two biologically active analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Equilibrium denaturation of insulin and proinsulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical studies on proinsulin — Association behavior and conformation in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implications of invariant residue LeuB6 in insulin-receptor interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of an optimized refolding process for recombinant Ala-Glu-IGF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein folding bottlenecks: A lattice Monte Carlo simulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of invariant valine B12 in insulin: implications for receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Halogen-Bonding-Based Heteroditopic Receptor for Alkali Metal Halides

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical protein "un-design": insulin's intrachain disulfide bridge tethers a recognition alpha-helix

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of aliphatic side-chain structure at positions 2 and 3 of the insulin A chain in insulin-receptor interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and Biological Activity of Two Disulphide Bond Isomers of Human Insulin: [A7-A11 ,A6-B7-Cystine]- and [A6-A7,A11-B7-Cystine]insulin (Human)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folding of insulin-like growth factor I is thermodynamically controlled by insulin-like growth factor binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and biological activity of hagfish insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors that affect the folding ability of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disulfide exchange folding of disulfide mutants of insulin-like growth factor I in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine scanning mutagenesis of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the phenylalanine B25 side chain in directing insulin interaction with its receptor. Steric and conformational effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20663888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method to predict protein flexibility using secondary chemical shifts

1 reference

5 May 2024

https://opencitations.net/index/api/v1/citations/10.1021/JA054842F

Identifiers

10.1074/JBC.M110.152645

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663888%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663888%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663888%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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