(Q34182228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

0 references

Kathrin Stephanie Zeller

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

Anjum Riaz

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Staffan Johansson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

language of work or name

English

0 references

publication date

22 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

e32081

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

24 January 2020

copyright license

start time

22 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation

5 July 2018

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A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells

5 July 2018

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PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading.

5 July 2018

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Physiological regulation of Akt activity and stability.

5 July 2018

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The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

5 July 2018

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DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif

5 July 2018

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Scaffolding function of PAK in the PDK1-Akt pathway

5 July 2018

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The life of a cell: apoptosis regulation by the PI3K/PKB pathway

5 July 2018

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Anoikis: a necessary death program for anchorage-dependent cells

5 July 2018

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Freud-1/Aki1, a novel PDK1-interacting protein, functions as a scaffold to activate the PDK1/Akt pathway in epidermal growth factor signaling

5 July 2018

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PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

5 July 2018

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An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase

5 July 2018

1 reference

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AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition

5 July 2018

1 reference

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Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

5 July 2018

1 reference

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5 July 2018

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Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes

5 July 2018

1 reference

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PKB and the mitochondria: AKTing on apoptosis

5 July 2018

1 reference

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LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells

5 July 2018

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Signalling through Class I PI3Ks in mammalian cells

5 July 2018

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

5 July 2018

1 reference

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Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival

5 July 2018

1 reference

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Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors

5 July 2018

1 reference

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PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle

5 July 2018

1 reference

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Integrin alpha8beta1-fibronectin interactions promote cell survival via PI3 kinase pathway.

5 July 2018

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 July 2018

1 reference

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Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

5 July 2018

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AKT/PKB signaling mechanisms in cancer and chemoresistance

5 July 2018

1 reference

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Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM.

5 July 2018

1 reference

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

5 July 2018

1 reference

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Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

5 July 2018

1 reference

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G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

5 July 2018

1 reference

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Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Regulation of Akt/PKB activation by tyrosine phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284553

Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

EGFR and beta1 integrins utilize different signaling pathways to activate Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

Human intestinal epithelial cell survival and anoikis. Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

The Akt isoforms are present at distinct subcellular locations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

A molecular link between AKT regulation and chemotherapeutic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032081

10.1371/JOURNAL.PONE.0032081

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

22384145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384145%20AND%20SRC:MED&resulttype=core&format=json