(Q34185176)

31 July 2017

1 reference

title

Defective protein folding and aggregation as the basis of neurodegenerative diseases: the darker aspect of proteins (English)

1 reference

31 July 2017

0 references

1 reference

Aabgeena Naeem

1

1 reference

31 July 2017

Naveed Ahmad Fazili

series ordinal

2

1 reference

31 July 2017

publication date

1 November 2011

1 reference

Cell Biochemistry and Biophysics

31 July 2017

published in

1 reference

31 July 2017

volume

61

1 reference

31 July 2017

issue

2

1 reference

31 July 2017

page(s)

237-250

1 reference

Theory of protein folding

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The formation and stabilization of protein structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The design and characterization of two proteins with 88% sequence identity but different structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular mechanisms of acid denaturation. The role of histidine residues in the partial unfolding of apomyoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein folding: local structures, domains, subunits, and assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Partially folded intermediate state of concanavalin A retains its carbohydrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Role of electrostatic repulsion in the acidic molten globule of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Conformational changes induced in lens alpha- and gamma-crystallins by modification with glucose 6-phosphate. Implications for cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Folding of a nascent peptide on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The Hsp70 and Hsp60 chaperone machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Enzymes that catalyse the restructuring of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein folding and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

A backbone-based theory of protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Is the molten globule a third phase of proteins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Unfolding the role of protein misfolding in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Different conformations for the same polypeptide bound to chaperones DnaK and GroEL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein folding in the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein folding in the cell: the role of molecular chaperones Hsp70 and Hsp60

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The structural basis of protein folding and its links with human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Potent antitumour activity of a new class of tumour-specific killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Defective protein folding as a basis of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

CFTR and chaperones: processing and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Characterization of the nanoscale properties of individual amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Diffraction to study protein and peptide assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Structural diversity of ex vivo amyloid fibrils studied by cryo-electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The protofilament structure of insulin amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

From the globular to the fibrous state: protein structure and structural conversion in amyloid formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Mutational analysis of the structural organization of polyglutamine aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Polyglutamine fibrillogenesis: the pathway unfolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein folding and aggregation in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Intrinsic disorder in proteins associated with neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular chaperones and protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Hsp27 negatively regulates cell death by interacting with cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein degradation, aggregation, and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The biochemistry of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cell death: protein misfolding and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The missing zinc: p53 misfolding and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular mechanisms of nitrosative stress-mediated protein misfolding in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Post-translational modifications of tubulin in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein misfolding, functional amyloid, and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

A portrait of Alzheimer secretases--new features and familiar faces

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Alzheimer's disease: treatments in discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

CHIP targets toxic alpha-Synuclein oligomers for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein aggregation and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Progression of symptoms in the early and middle stages of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein aggregation in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Crystallin proteins and amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Identification of the primary targets of carbamylation in bovine lens proteins by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Genetics of crystallins: cataract and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The Structure of the Cataract-Causing P23T Mutant of Human γD-Crystallin Exhibits Distinctive Local Conformational and Dynamic Changes † , ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cystic fibrosis: a disease of altered protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Inhibition of transthyretin amyloid fibril formation by 2,4-dinitrophenol through tetramer stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Protein aggregation and amyloid fibril formation by an SH3 domain probed by limited proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Insights into the amyloid folding problem from solid-state NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

The protofilament substructure of amyloid fibrils11Edited by F. E. Cohen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Molecular Evidence for the Involvement of Alpha Crystallin in the Colouration/Crosslinking of Crystallins in Age-related Nuclear Cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Peptide-binding specificity of the molecular chaperone BiP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9200-X

10.1007/S12013-011-9200-X

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

31 July 2017

1039196088

0 references

1 reference