(Q34466014)

2 August 2017

title

Polyglutamine fibrillogenesis: the pathway unfolds (English)

1 reference

2 August 2017

4

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2 August 2017

Erich E Wanker

3

0 references

Christopher A Ross

series ordinal

1

object named as

Christopher A Ross

1 reference

2 August 2017

Michelle A Poirier

2

1 reference

2 August 2017

language of work or name

English

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publication date

30 December 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

100

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2 August 2017

issue

1

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2 August 2017

page(s)

1-3

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Mutational analysis of the structural organization of polyglutamine aggregates

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

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6 July 2018

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Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

6 July 2018

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A linear lattice model for polyglutamine in CAG-expansion diseases

6 July 2018

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6 July 2018

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Therapeutic strategies for human amyloid diseases

6 July 2018

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Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

6 July 2018

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Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.

6 July 2018

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Amyloid fibers are water-filled nanotubes

6 July 2018

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A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

6 July 2018

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Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity

6 July 2018

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Histone deacetylase inhibitors reduce polyglutamine toxicity

6 July 2018

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Polyglutamine expansion neurodegenerative disease

6 July 2018

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

6 July 2018

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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

6 July 2018

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Impairment of the ubiquitin-proteasome system by protein aggregation

6 July 2018

1 reference

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Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

6 July 2018

1 reference

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Beyond the Qs in the polyglutamine diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Aggresomes, inclusion bodies and protein aggregation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Nucleated conformational conversion and the replication of conformational information by a prion determinant

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

CREB-binding protein sequestration by expanded polyglutamine

6 July 2018

1 reference

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Glutamine repeats and neurodegeneration

6 July 2018

1 reference

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Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

6 July 2018

1 reference

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

6 July 2018

1 reference

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Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

6 July 2018

1 reference

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Amyloid fibrillogenesis: themes and variations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Glutamine repeats and neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Polar zippers: their role in human disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

When more is less: pathogenesis of glutamine repeat neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Folding of oligoglutamines: a theoretical approach based upon thermodynamics and molecular mechanics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

Huntington aggregates may not predict neuronal death in Huntington's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140861

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0237018100

21 January 2018

Identifiers

DOI

10.1073/PNAS.0237018100

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference