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Multi-targeted therapy of cancer by niclosamide: A new application for an old drug.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
title
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
main subject
niclosamide
1 reference
based on heuristic
inferred from title
author
Donald J Buchsbaum
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
author name string
Yonghe Li
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
Pui-Kai Li
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
Michael J Roberts
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
Rebecca C Arend
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
Rajeev S Samant
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
language of work or name
English
0 references
publication date
13 April 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
published in
Cancer Letters
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
volume
349
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
page(s)
8-14
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
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Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer.
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Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells
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Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents
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5 July 2018
Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production
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Growth inhibition of ovarian tumor-initiating cells by niclosamide.
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5 July 2018
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling
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5 July 2018
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5 July 2018
Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells
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Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress
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5 July 2018
Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway
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Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death
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S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells
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5 July 2018
Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer
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5 July 2018
Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations
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5 July 2018
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Targeting Hedgehog--a cancer stem cell pathway
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mTOR signaling and drug development in cancer
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5 July 2018
The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.
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Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling
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5 July 2018
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.
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MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1.
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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
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New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases
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Mutational analysis of acute-phase response factor/Stat3 activation and dimerization
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
5 July 2018
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
5 July 2018
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
5 July 2018
The biology and toxicology of molluscicides, Bayluscide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
5 July 2018
Salinomycin, a new polyether antibiotic.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
5 July 2018
Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
28 October 2018
The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4166407
retrieved
28 October 2018
The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24732808
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24732808
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CANLET.2014.04.003
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
PMC publication ID
4166407
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
PubMed publication ID
24732808
1 reference
stated in
Europe PubMed Central
PMC publication ID
4166407
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732808%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
ResearchGate publication ID
261735503
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