(Q34383442)

1 August 2017

title

Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction (English)

1 reference

1 August 2017

Hong-Gang Wang

8

0 references

Juan R Del Valle

10

object named as

Juan R Del Valle

1 reference

1 August 2017

Young B Kim

1

1 reference

1 August 2017

Maria E Balasis

2

1 reference

1 August 2017

Kenichiro Doi

3

1 reference

1 August 2017

Norbert Berndt

4

1 reference

1 August 2017

Courtney DuBoulay

5

1 reference

1 August 2017

Chih-Chi Andrew Hu

6

1 reference

1 August 2017

Wayne Guida

7

1 reference

1 August 2017

Saïd M Sebti

9

1 reference

1 August 2017

language of work or name

English

0 references

publication date

24 July 2012

1 reference

Bioorganic & Medicinal Chemistry Letters

1 August 2017

published in

1 reference

1 August 2017

volume

22

1 reference

1 August 2017

issue

18

1 reference

1 August 2017

page(s)

5961-5965

1 reference

Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

The BCL-2 protein family: opposing activities that mediate cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Structural insights into the degradation of Mcl-1 induced by BH3 domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Pyrogallol-based molecules as potent inhibitors of the antiapoptotic Bcl-2 proteins.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

The Bcl-2 apoptotic switch in cancer development and therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Life in the balance: how BH3-only proteins induce apoptosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

6 July 2018

At the gates of death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432503

BCL-2 gene family and the regulation of programmed cell death

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22901384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of apoptotic regulators and their significance in cervical cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22901384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22901384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2012.07.050

1 reference

1 August 2017

1 reference

1 August 2017

1 reference