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What are super-enhancers?
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1 reference
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Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
title
What are super-enhancers?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
author
Jason D Lieb
series ordinal
2
object named as
Jason D Lieb
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
author name string
Sebastian Pott
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
language of work or name
English
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publication date
1 January 2015
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Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
published in
Nature Genetics
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stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
volume
47
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
page(s)
8-12
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/ng.3167
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Expression of a β-globin gene is enhanced by remote SV40 DNA sequences
1 reference
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Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.
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A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene.
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A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes.
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Disentangling the many layers of eukaryotic transcriptional regulation
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Transcription factors: from enhancer binding to developmental control
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7 January 2021
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Functional and mechanistic diversity of distal transcription enhancers
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7 January 2021
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Transcriptional enhancers: from properties to genome-wide predictions
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Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor
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Looping and interaction between hypersensitive sites in the active beta-globin locus
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7 January 2021
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ChIP-seq accurately predicts tissue-specific activity of enhancers
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7 January 2021
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The accessible chromatin landscape of the human genome
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7 January 2021
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An integrated encyclopedia of DNA elements in the human genome
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7 January 2021
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Genome-wide mapping of in vivo protein-DNA interactions
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7 January 2021
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High-resolution profiling of histone methylations in the human genome
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7 January 2021
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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
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7 January 2021
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Mapping and analysis of chromatin state dynamics in nine human cell types
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7 January 2021
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A unique chromatin signature uncovers early developmental enhancers in humans
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Histone H3K27ac separates active from poised enhancers and predicts developmental state
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Genome-wide chromatin state transitions associated with developmental and environmental cues
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Rapid and pervasive changes in genome-wide enhancer usage during mammalian development
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Master transcription factors and mediator establish super-enhancers at key cell identity genes
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7 January 2021
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Super-enhancers in the control of cell identity and disease
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7 January 2021
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Selective inhibition of tumor oncogenes by disruption of super-enhancers
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7 January 2021
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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Mediator and cohesin connect gene expression and chromatin architecture
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Crossref
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.
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Crossref
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Epigenomic enhancer profiling defines a signature of colon cancer
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.
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7 January 2021
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The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
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7 January 2021
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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
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7 January 2021
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BET bromodomain inhibition as a therapeutic strategy to target c-Myc
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7 January 2021
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Targeting MYC dependence in cancer by inhibiting BET bromodomains
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus
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7 January 2021
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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
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7 January 2021
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
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7 January 2021
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Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
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7 January 2021
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Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
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7 January 2021
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Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma.
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus.
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Systematic localization of common disease-associated variation in regulatory DNA
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Chromatin marks identify critical cell types for fine mapping complex trait variants
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Epigenomic analysis of multilineage differentiation of human embryonic stem cells
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Locus control regions
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7 January 2021
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Position-independent, high-level expression of the human beta-globin gene in transgenic mice
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7 January 2021
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A map of open chromatin in human pancreatic islets
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
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7 January 2021
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Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Shadow enhancers foster robustness of Drosophila gastrulation
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7 January 2021
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Phenotypic robustness conferred by apparently redundant transcriptional enhancers
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7 January 2021
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Animal transcription networks as highly connected, quantitative continua
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7 January 2021
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DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila
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7 January 2021
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A transcription factor collective defines cardiac cell fate and reflects lineage history
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7 January 2021
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A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives.
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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A gene complex controlling segmentation in Drosophila
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes
1 reference
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7 January 2021
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Modulating Hox gene functions during animal body patterning
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7 January 2021
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Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues.
1 reference
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Widespread misinterpretable ChIP-seq bias in yeast
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7 January 2021
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Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
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Where does mediator bind in vivo?
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7 January 2021
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Genome-scale CRISPR-Cas9 knockout screening in human cells
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https://api.crossref.org/works/10.1038%2FNG.3167
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7 January 2021
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Identifiers
DOI
10.1038/NG.3167
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
Dimensions Publication ID
1004271118
0 references
PubMed ID
25547603
1 reference
stated in
Europe PubMed Central
PubMed ID
25547603
retrieved
2 August 2017
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