(Q34595154)

English

A decreased level of serum soluble Klotho is an independent biomarker associated with arterial stiffness in patients with chronic kidney disease

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

A decreased level of serum soluble Klotho is an independent biomarker associated with arterial stiffness in patients with chronic kidney disease (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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chronic renal insufficiency

1 reference

based on heuristic

inferred from title

Hitoshi Sugiyama

2

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Europe PubMed Central

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24 February 2020

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Masashi Kitagawa

1

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24 February 2020

Hiroshi Morinaga

3

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24 February 2020

Tatsuyuki Inoue

4

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24 February 2020

Keiichi Takiue

5

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24 February 2020

Ayu Ogawa

6

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24 February 2020

Toshio Yamanari

7

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24 February 2020

Yoko Kikumoto

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Haruhito Adam Uchida

9

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24 February 2020

Shinji Kitamura

10

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24 February 2020

Yohei Maeshima

11

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24 February 2020

Kazufumi Nakamura

12

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24 February 2020

Hiroshi Ito

13

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24 February 2020

Hirofumi Makino

14

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24 February 2020

language of work or name

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publication date

19 February 2013

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24 February 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

8

1 reference

Europe PubMed Central

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24 February 2020

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

e56695

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

copyright license

Creative Commons Attribution 4.0 International

19 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Plasma Klotho is not related to kidney function and does not predict adverse outcome in patients with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Serum high-sensitivity cardiac troponin T is a significant biomarker of left-ventricular diastolic dysfunction in subjects with non-diabetic chronic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Regulation and function of the FGF23/klotho endocrine pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Effluent free radicals are associated with residual renal function and predict technique failure in peritoneal dialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Plasma klotho and cardiovascular disease in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Role of Klotho in aging, phosphate metabolism, and CKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Plasma klotho and mortality risk in older community-dwelling adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Phosphate and Klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho deficiency causes vascular calcification in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Forging forward with 10 burning questions on FGF23 in kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Aortic PWV in chronic kidney disease: a CRIC ancillary study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Revised equations for estimated GFR from serum creatinine in Japan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Improving global outcomes in mineral and bone disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

alpha-Klotho as a regulator of calcium homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Klotho converts canonical FGF receptor into a specific receptor for FGF23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Regulation of fibroblast growth factor-23 signaling by klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Suppression of aging in mice by the hormone Klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Preventi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

Ultrasonic evaluation of early carotid atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

7 July 2018

FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patients.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Klotho protein protects against endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Validation of an immunoassay for soluble Klotho protein: decreased levels in diabetes and increased levels in chronic kidney disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Severely reduced production of klotho in human chronic renal failure kidney.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Assessment and significance of abdominal aortic calcification in chronic kidney disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Improved assessment of aortic calcification in Japanese patients undergoing maintenance hemodialysis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Ezetimibe improves postprandial hyperlipemia and its induced endothelial dysfunction.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Large-artery stiffness: a reversible marker of cardiovascular risk in primary hyperparathyroidism

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Pulse wave velocity in primary hyperparathyroidism and effect of surgical therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

FGF23 is independently associated with vascular calcification but not bone mineral density in patients at various CKD stages.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Exposure to Uremic Serum Induces a Procalcific Phenotype in Human Mesenchymal Stem Cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Serum phosphate levels and mortality risk among people with chronic kidney disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Brachial-Ankle Pulse Wave Velocity as a Marker of Atherosclerotic Vascular Damage and Cardiovascular Risk

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

High phosphate directly affects endothelial function by downregulating annexin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576368

27 October 2018

Combined Use of Vitamin D Status and FGF23 for Risk Stratification of Renal Outcome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056695

21 January 2018

Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of phosphate on vascular function under normal conditions and influence of the uraemic state

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF-23 and osteoprotegerin are independently associated with myocardial damage in chronic kidney disease stages 3 and 4. Another link between chronic kidney disease-mineral bone disorder and the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of ankle-brachial index, brachial-ankle pulse wave velocity, flow-mediated dilation, and nitroglycerin-mediated dilation in end-stage renal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cinacalcet treatment on serum soluble Klotho levels in haemodialysis patients with secondary hyperparathyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arterial stiffness and enlargement in mild-to-moderate chronic kidney disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mineral metabolism and arterial functions in end-stage renal disease: potential role of 25-hydroxyvitamin D deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum soluble α-klotho in hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid pulse therapy impaired endothelial function while increasing plasma high molecule adiponectin concentration in patients with IgA nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum phosphate is associated with left ventricular mass in patients with chronic kidney disease: a cardiac magnetic resonance study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0056695

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

2013PLoSO...856695K

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23431388%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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