(Q34637225)

3 August 2017

title

Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy (SBMA). (English)

1 reference

3 August 2017

1 reference

5

Gen Sobue

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3 August 2017

Haruhiko Banno

1

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3 August 2017

Masahisa Katsuno

series ordinal

2

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3 August 2017

Keisuke Suzuki

series ordinal

3

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3 August 2017

Fumiaki Tanaka

series ordinal

4

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3 August 2017

publication date

4 April 2012

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3 August 2017

published in

Cell and Tissue Research

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3 August 2017

volume

349

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3 August 2017

issue

1

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3 August 2017

page(s)

313-320

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Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.

3 August 2017

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Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: a pathogenic marker

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Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

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Assessing the quality of reports of randomized clinical trials: is blinding necessary?

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Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

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21 January 2018

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21 January 2018

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Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophy

21 January 2018

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Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

21 January 2018

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Absence of disturbed axonal transport in spinal and bulbar muscular atrophy

21 January 2018

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CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

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Identifying polyglutamine protein species in situ that best predict neurodegeneration

21 January 2018

1 reference

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Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

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Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease.

21 January 2018

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Autophagy and access: understanding the role of androgen receptor subcellular localization in SBMA.

21 January 2018

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Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy

21 January 2018

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JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport

21 January 2018

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Native functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy

21 January 2018

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An Interdomain Interaction of the Androgen Receptor Is Required for Its Aggregation and Toxicity in Spinal and Bulbar Muscular Atrophy

21 January 2018

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Preparing for preventive clinical trials: the Predict-HD study

21 January 2018

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The polyglutamine tract of androgen receptor: from functions to dysfunctions in motor neurons.

21 January 2018

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Effect of aerobic training in patients with spinal and bulbar muscular atrophy (Kennedy disease).

21 January 2018

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Mitochondrial abnormalities in spinal and bulbar muscular atrophy

21 January 2018

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

21 January 2018

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Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction

21 January 2018

1 reference

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17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

21 January 2018

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21 January 2018

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

21 January 2018

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21 January 2018

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21 January 2018

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ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

21 January 2018

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10.1007/S00441-012-1377-9

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

3 August 2017

1000525589

0 references

1 reference