(Q34662167)

3 August 2017

title

WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells (English)

1 reference

3 August 2017

1 reference

Benjamin Yeung

1

1 reference

3 August 2017

King-Ching Ho

series ordinal

2

1 reference

3 August 2017

Xiaolong Yang

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

3 April 2013

1 reference

3 August 2017

1 reference

3 August 2017

volume

8

1 reference

3 August 2017

issue

4

1 reference

3 August 2017

page(s)

e61027

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

3 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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WWP1: a versatile ubiquitin E3 ligase in signaling and diseases

7 July 2018

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

7 July 2018

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WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts

7 July 2018

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Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]

7 July 2018

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A novel oncoprotein Pirh2: rising from the shadow of MDM2.

7 July 2018

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KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases

7 July 2018

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Hippo signaling at a glance

7 July 2018

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LATS tumor suppressor: a new governor of cellular homeostasis

7 July 2018

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Modularity in the Hippo signaling pathway

7 July 2018

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The ubiquitin pathway: an emerging drug target in cancer therapy

7 July 2018

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Molecular characterization of human homologs of yeast MOB1

7 July 2018

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WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

7 July 2018

1 reference

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Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

7 July 2018

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The HECT family of E3 ubiquitin ligases: multiple players in cancer development

7 July 2018

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A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

7 July 2018

1 reference

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The Nedd4-like family of E3 ubiquitin ligases and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The amplified WWP1 gene is a potential molecular target in breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The E3 ubiquitin ligase Itch controls the protein stability of p63

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

WW domains provide a platform for the assembly of multiprotein networks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The ubiquitin-protein ligase Itch regulates p73 stability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Mdm2 association with p53 targets its ubiquitination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The MDM2 gene amplification database

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616014

Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061027

The Hippo pathway--from top to bottom and everything in between.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061027

SnapShot: The hippo signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061027

Overexpression of WWP1 is associated with the estrogen receptor and insulin-like growth factor receptor 1 in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061027

Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23573293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumour-promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23573293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23573293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0061027

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference