(Q34674256)

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Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

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19 January 2020

Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924 (English)

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19 January 2020

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Takeo Nakanishi

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19 January 2020

Scott H Kaufmann

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19 January 2020

Charles Erlichman

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Charles Erlichman

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19 January 2020

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Xiaonan Hou

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19 January 2020

Fei Huang

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19 January 2020

Joan M Carboni

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19 January 2020

Karen Flatten

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19 January 2020

Yan W Asmann

5

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19 January 2020

Cynthia Ten Eyck

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19 January 2020

Jennifer D Tibodeau

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19 January 2020

Douglas D Ross

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19 January 2020

Marco M Gottardis

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19 January 2020

Paul Haluska

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19 January 2020

publication date

1 January 2011

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19 January 2020

Molecular Cancer Therapeutics

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19 January 2020

10

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19 January 2020

1

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19 January 2020

117-125

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19 January 2020

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.

1 reference

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Targeting insulin-like growth factor type 1 receptor in cancer therapy.

1 reference

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7 July 2018

Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.

1 reference

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7 July 2018

Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development

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7 July 2018

Resistance pathways relevant to insulin-like growth factor-1 receptor-targeted therapy.

1 reference

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7 July 2018

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7 July 2018

Clinical development of inhibitors of the insulin-like growth factor receptor in oncology

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7 July 2018

The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors

1 reference

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7 July 2018

Insulin and insulin-like growth factor signalling in neoplasia

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IGF-1 receptor inhibitors in clinical trials--early lessons

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7 July 2018

The type 1 insulin-like growth factor receptor pathway

1 reference

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7 July 2018

HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.

1 reference

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Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity.

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Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

1 reference

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7 July 2018

In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.

1 reference

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ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal

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Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

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7 July 2018

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7 July 2018

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions

1 reference

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Differential and Special Properties of the Major Human UGT1-encoded Gastrointestinal UDP-glucuronosyltransferases Enhance Potential to Control Chemical Uptake

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1 reference

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A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

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1 reference

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10.1158/1535-7163.MCT-10-0438

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19 January 2020

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19 January 2020

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19 January 2020

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