(Q34695826)

4 August 2017

P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends (English)

1 reference

4 August 2017

Brandy Verhalen

1

1 reference

4 August 2017

Stephan Wilkens

series ordinal

2

1 reference

4 August 2017

language of work or name

English

0 references

publication date

28 January 2011

1 reference

Journal of Biological Chemistry

4 August 2017

1 reference

4 August 2017

286

1 reference

4 August 2017

10476-10482

1 reference

4 August 2017

12

1 reference

describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3060501/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Characterization of an asymmetric occluded state of P-glycoprotein with two bound nucleotides: implications for catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Alternating Access in Maltose Transporter Mediated by Rigid-Body Rotations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

ABC transporters: the power to change

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

ABC multidrug transporters: structure, function and role in chemoresistance.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Crystal structure of a catalytic intermediate of the maltose transporter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Flexibility in the ABC transporter MsbA: Alternating access with a twist

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Clustal W and Clustal X version 2.0

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Structure of an ABC transporter in complex with its binding protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Structure of a bacterial multidrug ABC transporter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

The remarkable transport mechanism of P-glycoprotein: a multidrug transporter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Disulfide cross-linking reveals a site of stable interaction between C-terminal regulatory domains of the two MalK subunits in the maltose transport complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Multidrug resistance in cancer: role of ATP-dependent transporters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

The human ATP-binding cassette (ABC) transporter superfamily.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

The catalytic cycle of P-glycoprotein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060501

P-glycoprotein catalytic mechanism: studies of the ADP-vanadate inhibited state

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Catalytic cycle of ATP hydrolysis by P-glycoprotein: evidence for formation of the E.S reaction intermediate with ATP-gamma-S, a nonhydrolyzable analogue of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Nucleotide binding to the multidrug resistance P-glycoprotein as studied by ESR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Expression, purification, and characterization of cysteine-free mouse P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Projection structure of P-glycoprotein by electron microscopy. Evidence for a closed conformation of the nucleotide binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Nucleotide-induced structural changes in P-glycoprotein observed by electron microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.193151

High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21278250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.193151

1 reference

4 August 2017

1 reference

4 August 2017

1 reference