(Q34762265)

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The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas

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Europe PubMed Central

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4 August 2017

The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas (English)

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4 August 2017

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Steven A Belinsky

17

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Steven A Belinsky

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4 August 2017

Frank D Gilliland

15

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Frank D Gilliland

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4 August 2017

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Shuguang Leng

1

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4 August 2017

Amanda M Bernauer

2

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4 August 2017

Chibo Hong

3

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4 August 2017

Kieu C Do

4

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4 August 2017

Christin M Yingling

5

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4 August 2017

Kristina G Flores

6

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4 August 2017

Mathewos Tessema

7

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4 August 2017

Carmen S Tellez

8

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4 August 2017

Randall P Willink

9

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4 August 2017

Elizabeth A Burki

10

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4 August 2017

Maria A Picchi

11

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4 August 2017

Christine A Stidley

12

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4 August 2017

Michael D Prados

13

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4 August 2017

Joseph F Costello

14

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Richard E Crowell

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publication date

25 February 2011

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4 August 2017

Clinical Cancer Research

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4 August 2017

17

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4 August 2017

7

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4 August 2017

2014-2023

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4 August 2017

Mechanisms of differential expression of the CYP2A13 7520C and 7520G alleles in human lung: allelic expression analysis for CYP2A13 heterogeneous nuclear RNA, and evidence for the involvement of multiple cis-regulatory single nucleotide polymorphism

1 reference

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7 July 2018

The 1000 Genomes Project: new opportunities for research and social challenges

1 reference

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Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers

1 reference

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

1 reference

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7 July 2018

Non-imprinted allele-specific DNA methylation on human autosomes.

1 reference

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Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

1 reference

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Lung cancer in never smokers: molecular profiles and therapeutic implications

1 reference

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Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

1 reference

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A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation

1 reference

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A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

1 reference

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7 July 2018

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

1 reference

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7 July 2018

An Sp1/Sp3 binding polymorphism confers methylation protection.

1 reference

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7 July 2018

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

1 reference

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7 July 2018

GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas.

1 reference

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7 July 2018

PGA: power calculator for case-control genetic association analyses.

1 reference

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7 July 2018

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070839

7 July 2018

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.

1 reference

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7 July 2018

DNA damage, homology-directed repair, and DNA methylation

1 reference

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Epigenetic stem cell signature in cancer

1 reference

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Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

1 reference

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Control of developmental regulators by Polycomb in human embryonic stem cells

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Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer

1 reference

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7 July 2018

Gene-promoter hypermethylation as a biomarker in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070839

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Polymorphisms in TDG and MGMT genes - epidemiological and functional study in lung cancer patients from Poland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070839

7 July 2018

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070839

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Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer

1 reference

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A comparison of bayesian methods for haplotype reconstruction from population genotype data

1 reference

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Predicting aberrant CpG island methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070839

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Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study

1 reference

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Novel O6-methylguanine-DNA methyltransferase SNPs: a frequency comparison of patients with familial melanoma and healthy individuals in Sweden

1 reference

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1 reference

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Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferase gene

1 reference

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CpG islands and genes

1 reference

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Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.

1 reference

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1 reference

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1 reference

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MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer

1 reference

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1 reference

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1 reference

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Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21355081

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-10-3026

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Europe PubMed Central

PubMed publication ID

4 August 2017

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Europe PubMed Central

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4 August 2017

PubMed publication ID

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4 August 2017

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