(Q34768898)

4 August 2017

1 reference

title

Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases (English)

1 reference

4 August 2017

2

1 reference

4 August 2017

Snezana Djordjevic

1

1 reference

PubMed ID

12151228

4 August 2017

language of work or name

1 reference

1 August 2002

1 reference

4 August 2017

7

1 reference

Trends in Biochemical Sciences

inferred from page(s)

published in

1 reference

4 August 2017

27

1 reference

4 August 2017

8

1 reference

4 August 2017

426-432

1 reference

Structural insights into phosphoinositide 3-kinase catalysis and signalling

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

PI3-kinase inhibition: a target for drug development?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Resistance to thromboembolism in PI3Kgamma-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Phospatidylinositol 3-kinase expression in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Structure of importin-beta bound to the IBB domain of importin-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Phox homology domains specifically bind phosphatidylinositol phosphates.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Interaction of Ras with phosphoinositide 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The activation of phosphatidylinositol 3-kinase by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Regulation of Ras signaling by the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Structural basis for the interaction of Ras with RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Crystal structure of P13K SH3 domain at 20 angstroms resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

NMR trial models: experiences with the colicin immunity protein Im7 and the p85alpha C-terminal SH2-peptide complex

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902136-9

7 January 2021

10.1016/S0968-0004(02)02136-9

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12151228