(Q34769889)

English

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

4 August 2017

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1 (English)

1 reference

Europe PubMed Central

4 August 2017

medulloblastoma

0 references

Wilfried Nietfeld

11

object named as

Wilfried Nietfeld

0 references

12

object named as

Hans Lehrach

1 reference

Europe PubMed Central

4 August 2017

2

object named as

Daniela Berg

1 reference

Europe PubMed Central

4 August 2017

16

object named as

Ulrike Korf

1 reference

Europe PubMed Central

4 August 2017

author name string

Frank Götschel

1

1 reference

Europe PubMed Central

4 August 2017

Wolfgang Gruber

3

1 reference

Europe PubMed Central

4 August 2017

Christian Bender

4

1 reference

Europe PubMed Central

4 August 2017

Markus Eberl

5

1 reference

Europe PubMed Central

4 August 2017

Myriam Friedel

6

1 reference

Europe PubMed Central

4 August 2017

Johanna Sonntag

7

1 reference

Europe PubMed Central

4 August 2017

Elena Rüngeler

8

1 reference

Europe PubMed Central

4 August 2017

Hendrik Hache

9

1 reference

Europe PubMed Central

4 August 2017

Christoph Wierling

10

1 reference

Europe PubMed Central

4 August 2017

Wilfried Nietfeld

11

1 reference

Europe PubMed Central

4 August 2017

Annemarie Frischauf

13

1 reference

Europe PubMed Central

4 August 2017

Reinhard Schwartz-Albiez

14

1 reference

Europe PubMed Central

4 August 2017

Fritz Aberger

15

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

10 June 2013

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

8

1 reference

Europe PubMed Central

4 August 2017

e65403

1 reference

Europe PubMed Central

4 August 2017

6

1 reference

Europe PubMed Central

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

10 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The crosstalk of mTOR/S6K1 and Hedgehog pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Cooperative Hedgehog-EGFR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Matrix metalloproteinases in tumorigenesis: an evolving paradigm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

RAS and Hedgehog--partners in crime

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Antiangiogenic strategies in medulloblastoma: reality or mystery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The Gli code: an information nexus regulating cell fate, stemness and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Infrared-based protein detection arrays for quantitative proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Hedgehog signal transduction: signal integration and cross talk in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

GLI transcription factors: mediators of oncogenic Hedgehog signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Small molecule modulation of Smoothened activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065403

21 January 2018

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065403

21 January 2018

Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065403

21 January 2018

Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065403

21 January 2018

Angiogenic profile of childhood primitive neuroectodermal brain tumours/medulloblastomas.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065403

21 January 2018

The role of cytokines in angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23762360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-8 is an angiogenic factor in human coronary atherectomy tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23762360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23762360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0065403

1 reference

Europe PubMed Central

4 August 2017

2013PLoSO...865403G

0 references

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34769889&oldid=1955244637"