(Q34769889)

English

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1 (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

medulloblastoma

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Wilfried Nietfeld

11

object named as

Wilfried Nietfeld

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12

object named as

Hans Lehrach

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2

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Daniela Berg

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Europe PubMed Central

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4 August 2017

16

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Ulrike Korf

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Europe PubMed Central

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4 August 2017

author name string

Frank Götschel

1

1 reference

Europe PubMed Central

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4 August 2017

Wolfgang Gruber

3

1 reference

Europe PubMed Central

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4 August 2017

Christian Bender

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Markus Eberl

5

1 reference

Europe PubMed Central

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4 August 2017

Myriam Friedel

6

1 reference

Europe PubMed Central

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4 August 2017

Johanna Sonntag

7

1 reference

Europe PubMed Central

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4 August 2017

Elena Rüngeler

8

1 reference

Europe PubMed Central

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4 August 2017

Hendrik Hache

9

1 reference

Europe PubMed Central

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4 August 2017

Christoph Wierling

10

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Wilfried Nietfeld

11

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Annemarie Frischauf

13

1 reference

Europe PubMed Central

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4 August 2017

Reinhard Schwartz-Albiez

14

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4 August 2017

Fritz Aberger

15

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4 August 2017

language of work or name

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publication date

10 June 2013

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Europe PubMed Central

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4 August 2017

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Europe PubMed Central

PubMed publication ID

4 August 2017

8

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Europe PubMed Central

PubMed publication ID

4 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

e65403

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

10 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs

1 reference

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1 reference

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The crosstalk of mTOR/S6K1 and Hedgehog pathways

1 reference

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Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

1 reference

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Cooperative Hedgehog-EGFR signaling

1 reference

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Matrix metalloproteinases in tumorigenesis: an evolving paradigm.

1 reference

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RAS and Hedgehog--partners in crime

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Hallmarks of Cancer: The Next Generation

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Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors

1 reference

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Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies

1 reference

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Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

1 reference

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Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

1 reference

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

1 reference

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7 July 2018

Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes

1 reference

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7 July 2018

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

1 reference

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7 July 2018

Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.

1 reference

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Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype.

1 reference

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Antiangiogenic strategies in medulloblastoma: reality or mystery.

1 reference

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7 July 2018

The Gli code: an information nexus regulating cell fate, stemness and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells

1 reference

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7 July 2018

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

7 July 2018

Infrared-based protein detection arrays for quantitative proteomics

1 reference

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7 July 2018

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677915

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Hedgehog signal transduction: signal integration and cross talk in development and cancer

1 reference

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Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

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GLI transcription factors: mediators of oncogenic Hedgehog signalling

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Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

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Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.

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Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

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The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8.

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Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.

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Small molecule modulation of Smoothened activity

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The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

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1 reference

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1 reference

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1 reference

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Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

1 reference

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Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

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based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23762360

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1 reference

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Identifiers

10.1371/JOURNAL.PONE.0065403

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2013PLoSO...865403G

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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