(Q34940694)

5 August 2017

Interactions of the multidrug resistance modulators tariquidar and elacridar and their analogues with P-glycoprotein (English)

1 reference

5 August 2017

multiple drug resistance

1 reference

1

Ilza K Pajeva

1 reference

5 August 2017

Katja Sterz

2

1 reference

5 August 2017

Matthias Christlieb

3

1 reference

5 August 2017

Kerstin Steggemann

4

1 reference

5 August 2017

Federico Marighetti

5

1 reference

5 August 2017

Michael Wiese

6

1 reference

5 August 2017

13 August 2013

1 reference

5 August 2017

1 reference

5 August 2017

8

1 reference

5 August 2017

10

1 reference

5 August 2017

1701-1713

1 reference

The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research

5 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Enhancement of vincristine- and adriamycin-induced cytotoxicity by verapamil in P388 leukemia and its sublines resistant to vincristine and adriamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Inhibition of P-glycoprotein function by XR9576 in a solid tumour model can restore anticancer drug efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Functional assay and structure-activity relationships of new third-generation P-glycoprotein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Novel lead for potent inhibitors of breast cancer resistance protein (BCRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Specific inhibitors of the breast cancer resistance protein (BCRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure-activity relationships of a series of tariquidar analogs as multidrug resistance modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure-activity relationships of tariquidar analogs as multidrug resistance modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Identification of putative binding sites of P-glycoprotein based on its homology model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Combined pharmacophore modeling, docking, and 3D QSAR studies of ABCB1 and ABCC1 transporter inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Comparison of the inward- and outward-open homology models and ligand binding of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure of a bacterial multidrug ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Protein contacts and ligand binding in the inward-facing model of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Activators of P-glycoprotein: Structure-activity relationships and investigation of their mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

The Protein Data Bank: a computer-based archival file for macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

COSMO: a new approach to dielectric screening in solvents with explicit expressions for the screening energy and its gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

What are the dielectric "constants" of proteins and how to validate electrostatic models?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Catalytic transitions in the human MDR1 P-glycoprotein drug binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Proximity of bound Hoechst 33342 to the ATPase catalytic sites places the drug binding site of P-glycoprotein within the cytoplasmic membrane leaflet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

New functional assay of P-glycoprotein activity using Hoechst 33342.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

RM1: a reparameterization of AM1 for H, C, N, O, P, S, F, Cl, Br, and I

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

inferred from DOI database lookup

7 January 2021

based on heuristic

Communication between multiple drug binding sites on P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

inferred from DOI database lookup

7 January 2021

based on heuristic

Two transport binding sites of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300233

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/CMDC.201300233

1 reference

5 August 2017

1 reference