(Q42638072)

4 November 2017

title

Comparison of the inward- and outward-open homology models and ligand binding of human P-glycoprotein (English)

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4 November 2017

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1

Ilza K Pajeva

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4 November 2017

2

Christoph Globisch

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4 November 2017

Michael Wiese

3

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4 November 2017

language of work or name

English

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publication date

29 October 2009

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4 November 2017

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4 November 2017

volume

276

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4 November 2017

issue

23

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4 November 2017

page(s)

7016-7026

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

4 November 2017

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The role of ABC transporters in drug resistance, metabolism and toxicity

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Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil

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Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

21 January 2018

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Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.

21 January 2018

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Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein

21 January 2018

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Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites

21 January 2018

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Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

21 January 2018

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Quantification and characterization of P-glycoprotein-substrate interactions

21 January 2018

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Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket

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Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesis

21 January 2018

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Identification of putative binding sites of P-glycoprotein based on its homology model

21 January 2018

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Molecular models of human P-glycoprotein in two different catalytic states

21 January 2018

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

21 January 2018

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ATP occlusion by P-glycoprotein as a surrogate measure for drug coupling

21 January 2018

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Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity

21 January 2018

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Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

21 January 2018

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21 January 2018

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Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

21 January 2018

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Combined pharmacophore modeling, docking, and 3D QSAR studies of ABCB1 and ABCC1 transporter inhibitors

21 January 2018

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21 January 2018

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Development and validation of a genetic algorithm for flexible docking

21 January 2018

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2D depiction of protein-ligand complexes.

21 January 2018

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Flexible alignment of small molecules

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07415.X

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

21 January 2018

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Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07415.X

10.1111/J.1742-4658.2009.07415.X

21 January 2018

Identifiers

DOI

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4 November 2017

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