(Q34942330)

5 August 2017

1 reference

title

PTEN function in mammalian cell size regulation (English)

1 reference

5 August 2017

Vuk Stambolic

2

0 references

author name string

Stéphanie Backman

series ordinal

1

1 reference

PubMed ID

12367630

5 August 2017

Tak Mak

series ordinal

3

1 reference

5 August 2017

1 October 2002

1 reference

Current Opinion in Neurobiology

5 August 2017

1 reference

5 August 2017

12

1 reference

5 August 2017

516-522

1 reference

5 August 2017

5

1 reference

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Severe Lhermitte-Duclos disease with unique germline mutation of PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Lhermitte-Duclos disease as a component of Cowden's syndrome. Case report and review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Cowden disease and Lhermitte-Duclos disease: characterization of a new phakomatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Association of Lhermitte-Duclos and Cowden disease: report of a new case and review of the literature.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Regulation of translation initiation by FRAP/mTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Modulation of cellular apoptotic potential: contributions to oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

c-Myc regulates mammalian body size by controlling cell number but not cell size.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Conditional alleles in mice: practical considerations for tissue-specific knockouts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Immunohistochemistry and proliferative activity in Lhermitte-Duclos disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Genetic control of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Diversification of cell cycle controls in developing embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Cell cycle regulators in neural stem cells and postmitotic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

A role for nuclear PTEN in neuronal differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Extracellular control of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The radiological features of hemimegalencephaly including three cases associated with proteus syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Epidermal nevus syndrome: a neurologic variant with hemimegalencephaly, gyral malformation, mental retardation, seizures, and facial hemihypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Drosophila S6 kinase: a regulator of cell size.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Mammalian TOR: a homeostatic ATP sensor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The modular phosphorylation and activation of p70s6k.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

PDK1 regulates growth through Akt and S6K in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2802%2900354-9

7 January 2021

10.1016/S0959-4388(02)00354-9

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12367630