(Q34976286)

5 August 2017

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title

Death and survival of neuronal cells exposed to Alzheimer's insults (English)

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5 August 2017

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Takako Niikura

1

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5 August 2017

Yuichi Hashimoto

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2

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5 August 2017

Hirohisa Tajima

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3

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5 August 2017

Ikuo Nishimoto

series ordinal

4

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5 August 2017

1 November 2002

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Journal of Neuroscience Research

5 August 2017

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5 August 2017

70

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5 August 2017

3

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5 August 2017

380-391

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Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning

5 August 2017

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Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

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The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 January 2018

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CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

21 January 2018

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A femtomolar-acting neuroprotective peptide

21 January 2018

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Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

21 January 2018

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.

21 January 2018

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A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.

21 January 2018

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Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures.

21 January 2018

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Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.

21 January 2018

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The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

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The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

21 January 2018

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G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP.

21 January 2018

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Individual isoforms of the amyloid beta precursor protein demonstrate differential adhesive potentials to constituents of the extracellular matrix

21 January 2018

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

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Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

21 January 2018

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Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons.

21 January 2018

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Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

21 January 2018

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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

21 January 2018

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Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein

21 January 2018

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Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2.

21 January 2018

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Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target

21 January 2018

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Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

21 January 2018

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

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Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis

21 January 2018

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Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

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The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

21 January 2018

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Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

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Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

21 January 2018

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

21 January 2018

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[Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo

21 January 2018

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Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons.

21 January 2018

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Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway.

21 January 2018

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Enhancement of amyloid beta 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease.

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Alzheimer's disease: a dysfunction of the amyloid precursor protein(1).

21 January 2018

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V642I APP-inducible neuronal cells: a model system for investigating Alzheimer's disorders

21 January 2018

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Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

21 January 2018

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

21 January 2018

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The potential of BACE inhibitors for Alzheimer's therapy

21 January 2018

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

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Cell-specific expression of beta-amyloid precursor protein isoform mRNAs and proteins in neurons and astrocytes.

21 January 2018

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A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

21 January 2018

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Activation of caspase-8 in the Alzheimer's disease brain.

21 January 2018

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Oxidative stress, antioxidants, and Alzheimer disease

21 January 2018

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Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

21 January 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

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Amyloid peptides are toxic via a common oxidative mechanism

21 January 2018

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

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The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.

21 January 2018

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Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein

21 January 2018

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Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein

21 January 2018

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

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Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults

21 January 2018

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DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions

21 January 2018

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Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

21 January 2018

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beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

21 January 2018

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Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

21 January 2018

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Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection

21 January 2018

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Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

21 January 2018

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Regulation of apoptosis by presenilin 1.

21 January 2018

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G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

21 January 2018

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Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

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Overexpression of presenilin-2 enhances apoptotic death of cultured cortical neurons.

21 January 2018

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Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

21 January 2018

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Progressive dementia, without cerebral hemorrhage, in a patient with hereditary cerebral amyloid angiopathy

21 January 2018

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APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

21 January 2018

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Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.10354

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5 August 2017

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