(Q34997508)

5 August 2017

title

Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia (English)

1 reference

5 August 2017

0 references

1 reference

8

Carrie Sougnez

0 references

Gad Getz

24

Gad Getz

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Stacey Gabriel

17

Stacey Gabriel

1 reference

5 August 2017

19

Eric S Lander

1 reference

5 August 2017

23

Nir Hacohen

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Jean Fan

Jean Fan

5

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Kendell Clement

Kendell Clement

2

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Mahmoud Ghandi

Mahmoud Ghandi

13

0 references

Alexander Meissner

25

Alexander Meissner

1 reference

5 August 2017

14

Levi Garraway

1 reference

5 August 2017

22

Peter V Kharchenko

1 reference

5 August 2017

18

Andreas Gnirke

1 reference

5 August 2017

1

Dan A Landau

1 reference

5 August 2017

16

Kenneth J Livak

1 reference

5 August 2017

21

Donna Neuberg

1 reference

5 August 2017

Michael J Ziller

3

1 reference

5 August 2017

Patrick Boyle

4

1 reference

5 August 2017

Hongcang Gu

6

1 reference

5 August 2017

Kristen Stevenson

7

1 reference

5 August 2017

Lili Wang

9

1 reference

5 August 2017

Shuqiang Li

10

1 reference

5 August 2017

Dylan Kotliar

11

1 reference

5 August 2017

Wandi Zhang

12

1 reference

5 August 2017

Stacey M Fernandes

15

1 reference

5 August 2017

Jennifer R Brown

20

1 reference

5 August 2017

Catherine J Wu

26

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 December 2014

1 reference

5 August 2017

1 reference

5 August 2017

volume

26

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5 August 2017

issue

6

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5 August 2017

page(s)

813-825

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Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells

5 August 2017

cites work

1 reference

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Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

8 July 2018

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Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation

8 July 2018

1 reference

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8 July 2018

1 reference

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Clonal evolution in hematological malignancies and therapeutic implications

8 July 2018

1 reference

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Charting a dynamic DNA methylation landscape of the human genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Mutational heterogeneity in cancer and the search for new cancer-associated genes

8 July 2018

1 reference

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Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host

8 July 2018

1 reference

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Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Functions of DNA methylation: islands, start sites, gene bodies and beyond

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Regulated noise in the epigenetic landscape of development and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

A decade of exploring the cancer epigenome - biological and translational implications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Increased methylation variation in epigenetic domains across cancer types

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Cellular decision making and biological noise: from microbes to mammals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Hallmarks of Cancer: The Next Generation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DNMT3A Mutations in Acute Myeloid Leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DNA hypomethylation in cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Analysis of chronic lymphotic leukemia transcriptomic profile: differences between molecular subgroups

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Genome-scale DNA methylation maps of pluripotent and differentiated cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Module map of stem cell genes guides creation of epithelial cancer stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

The epigenomics of cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Epigenetic stem cell signature in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DNA methylation profiling of human chromosomes 6, 20 and 22

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DNA methylation and gene silencing in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

A census of mammalian imprinting.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Fidelity of the methylation pattern and its variation in the genome.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DNA methylation patterns and epigenetic memory

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

DCC protein expression in hematopoietic cell populations and its relation to leukemogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

Global gene expression profile of human cord blood-derived CD133+ cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302418

TCL1 is activated by chromosomal rearrangement or by hypomethylation

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25490447

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetic interactions between the Wilms' tumor 1 gene and the p53 gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25490447

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCELL.2014.10.012

1 reference

5 August 2017

1 reference

5 August 2017

1 reference