(Q35002331)

5 August 2017

title

Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven (English)

1 reference

Apoptosis and caspase activation inhibitor Dmel_CG15727

5 August 2017

main subject

Drosophila melanogaster

0 references

1 reference

GOA release 2020-03-11

Henry M Krause

8

0 references

Daniela Drummond-Barbosa

9

object named as

Daniela Drummond-Barbosa

1 reference

5 August 2017

Sige Zou

1

1 reference

5 August 2017

Joy Chang

2

1 reference

5 August 2017

Leesa LaFever

3

1 reference

5 August 2017

Wangli Tang

4

1 reference

5 August 2017

Erika L Johnson

5

1 reference

5 August 2017

Jack Hu

6

1 reference

5 August 2017

Ronit Wilk

7

1 reference

5 August 2017

Pablo M Irusta

10

1 reference

5 August 2017

publication date

15 March 2011

1 reference

5 August 2017

1 reference

5 August 2017

volume

10

1 reference

5 August 2017

issue

6

1 reference

5 August 2017

page(s)

989-998

1 reference

describes a project that uses

5 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3100878/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Regulation of the ATM-activator protein Aven by CRM1-dependent nuclear export

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Phylogeny and function of the invertebrate p53 superfamily

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Hormonal and nutritional regulation of insect fat body development and function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Cell-cycle control in the face of damage--a matter of life or death.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

DNA damage-induced cell death by apoptosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila damaged DNA-binding protein 1 is an essential factor for development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Telomere protection without a telomerase; the role of ATM and Mre11 in Drosophila telomere maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Regulation of Cdc25C activity during the meiotic G2/M transition.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drosophila p53 preserves genomic stability by regulating cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

GAL4 system in Drosophila: a fly geneticist's Swiss army knife

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The anaphase promoting complex/cyclosome is required during development for modified cell cycles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Preferential binding of ATR protein to UV-damaged DNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The pathogenesis of ataxia-telangiectasia. Learning from a Rosetta Stone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The role of ATM in DNA damage responses and cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Cell cycle checkpoints: preventing an identity crisis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Atm-deficient mice: a paradigm of ataxia telangiectasia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Periodic DNA synthesis in cell-free extracts of Xenopus eggs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The control of DNA replication in a cell-free extract that recapitulates a basic cell cycle in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Cyclin synthesis drives the early embryonic cell cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

8 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

ATM is required for telomere maintenance and chromosome stability during Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Relative contribution of DNA repair, cell cycle checkpoints, and cell death to survival after DNA damage in Drosophila larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

In vivo p53 function is indispensable for DNA damage-induced apoptotic signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Aven-dependent activation of ATM following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Specialized hepatocyte-like cells regulate Drosophila lipid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Survivin and aven: two distinct antiapoptotic signals in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Aven overexpression: association with poor prognosis in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

Control of fat storage by a Drosophila PAT domain protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.6.15080

When the checkpoints have gone: insights into Cdc25 functional activation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

reaper is required for neuroblast apoptosis during Drosophila development

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

The Drosophila gene morula inhibits mitotic functions in the endo cell cycle and the mitotic cell cycle.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100878

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21368576

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21368576

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.10.6.15080

1 reference

5 August 2017

1 reference

5 August 2017

1 reference