(Q35005738)

5 August 2017

Leptin induces IL-6 expression through OBRl receptor signaling pathway in human synovial fibroblasts (English)

1 reference

5 August 2017

Chun-Hao Tsai

3

0 references

author name string

Wei-Hung Yang

1

1 reference

5 August 2017

Shan-Chi Liu

2

1 reference

5 August 2017

Yi-Chin Fong

4

1 reference

5 August 2017

Shoou-Jyi Wang

5

1 reference

5 August 2017

Yung-Sen Chang

6

1 reference

5 August 2017

Chih-Hsin Tang

7

1 reference

5 August 2017

language of work or name

English

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publication date

27 September 2013

1 reference

5 August 2017

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5 August 2017

8

1 reference

5 August 2017

9

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5 August 2017

e75551

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

start time

27 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling

8 July 2018

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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

8 July 2018

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Lipid metabolism and osteoarthritis: lessons from atherosclerosis

8 July 2018

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The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

8 July 2018

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Leptin plays a catabolic role on articular cartilage

8 July 2018

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Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

8 July 2018

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8 July 2018

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Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts.

8 July 2018

1 reference

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Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia

8 July 2018

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Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism

8 July 2018

1 reference

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Increased expression of interleukin-6 by vasoactive intestinal peptide is associated with regulation of CREB, AP-1 and C/EBP, but not NF-kappaB, in mouse calvarial osteoblasts

8 July 2018

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Antiapoptotic effects of leptin in human neuroblastoma cells

8 July 2018

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Evidence for a key role of leptin in osteoarthritis

8 July 2018

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A role for leptin in rheumatic diseases?

8 July 2018

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8 July 2018

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Body mass indices in patients with disabling hip osteoarthritis

8 July 2018

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Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

8 July 2018

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Intracellular signalling. Key enzyme in leptin-induced anorexia

8 July 2018

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High-dose leptin activates human leukocytes via receptor expression on monocytes.

8 July 2018

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Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown

8 July 2018

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Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways

8 July 2018

1 reference

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Leptin in the regulation of immunity, inflammation, and hematopoiesis

8 July 2018

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

8 July 2018

1 reference

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Transcriptional regulation of the interleukin-6 gene in mesangial cells

8 July 2018

1 reference

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Unraveling the central nervous system pathways underlying responses to leptin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785513

Role of leptin in the neuroendocrine response to fasting

8 July 2018

1 reference

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Identification and expression cloning of a leptin receptor, OB-R

8 July 2018

1 reference

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Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8

8 July 2018

1 reference

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Interleukin-6 in autoimmune disease. Role of IL-6 in physiology and pathology of the immune defense

8 July 2018

1 reference

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Positional cloning of the mouse obese gene and its human homologue

8 July 2018

1 reference

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Nutritional modulation of cytokine biology

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

CCN4 induces vascular cell adhesion molecule-1 expression in human synovial fibroblasts and promotes monocyte adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Peptidoglycan enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, focal adhesion kinase, Akt, and AP-1- dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075551

Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis

21 January 2018

1 reference

12 December 2020

Adipocytokines in synovial fluid

1 reference

12 December 2020

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

1 reference

12 December 2020

Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway

1 reference

12 December 2020

Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter

1 reference

12 December 2020

Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage

1 reference

12 December 2020

Correlation of synovial fluid leptin concentrations with the severity of osteoarthritis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0075551

Identifiers

DOI

1 reference

release_d3tghkrfrvcgtghha2bxruheqy

5 August 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d3tghkrfrvcgtghha2bxruheqy

24 November 2022

mapped directly with Wikidata item

PMCID

3785513

1 reference

5 August 2017

1 reference