(Q35020704)

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Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulations

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Europe PubMed Central

PubMed publication ID

5 August 2017

Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulations (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Sharon Hammes-Schiffer

6

object named as

Sharon Hammes-Schiffer

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Europe PubMed Central

PubMed publication ID

5 August 2017

Jamie L Bingaman

4

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Jamie L Bingaman

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Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Sixue Zhang

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

Abir Ganguly

2

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Europe PubMed Central

PubMed publication ID

5 August 2017

Puja Goyal

3

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Europe PubMed Central

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5 August 2017

Philip C Bevilacqua

5

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Europe PubMed Central

PubMed publication ID

5 August 2017

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publication date

12 January 2015

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Europe PubMed Central

PubMed publication ID

5 August 2017

Journal of the American Chemical Society

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Europe PubMed Central

PubMed publication ID

5 August 2017

137

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Europe PubMed Central

PubMed publication ID

5 August 2017

2

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Europe PubMed Central

PubMed publication ID

5 August 2017

784-798

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4308743/fullTextXML

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Crystal structure and mechanistic investigation of the twister ribozyme

1 reference

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Altered (transition) states: mechanisms of solution and enzyme catalyzed RNA 2'-O-transphosphorylation

1 reference

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Evidence for the role of active site residues in the hairpin ribozyme from molecular simulations along the reaction path

1 reference

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Quantum mechanical/molecular mechanical free energy simulations of the self-cleavage reaction in the hepatitis delta virus ribozyme

1 reference

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A widespread self-cleaving ribozyme class is revealed by bioinformatics.

1 reference

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1 reference

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pH-dependent dynamics of complex RNA macromolecules

1 reference

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The glmS ribozyme cofactor is a general acid-base catalyst

1 reference

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General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.

1 reference

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QM/MM studies of hairpin ribozyme self-cleavage suggest the feasibility of multiple competing reaction mechanisms

1 reference

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An active-site guanine participates in glmS ribozyme catalysis in its protonated state

1 reference

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The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate

1 reference

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1 reference

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8 July 2018

Rapid steps in the glmS ribozyme catalytic pathway: cation and ligand requirements

1 reference

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An expanded collection and refined consensus model of glmS ribozymes

1 reference

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Analysis of metal ion dependence in glmS ribozyme self-cleavage and coenzyme binding

1 reference

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Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme

1 reference

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Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme

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1 reference

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8 July 2018

Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme

1 reference

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1 reference

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Essential role of an active-site guanine in glmS ribozyme catalysis

1 reference

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Autolytic processing of dimeric plant virus satellite RNA

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Requirement of Helix P2.2 and Nucleotide G1 for Positioning the Cleavage Site and Cofactor of the glmS Ribozyme

1 reference

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Coupling of fast and slow modes in the reaction pathway of the minimal hammerhead ribozyme cleavage

1 reference

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1 reference

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1 reference

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Advances in methods and algorithms in a modern quantum chemistry program package.

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Evidence for preorganization of the glmS ribozyme ligand binding pocket

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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based on heuristic

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Identifiers

10.1021/JA510387Y

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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