(Q35104777)

6 August 2017

title

Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold (English)

1 reference

6 August 2017

Daniel D Lam

1

0 references

Aaron J Mercer

object named as

Aaron J Mercer

9

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Flavio S J de Souza

object named as

Flavio S J de Souza

2

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author name string

Sofia Nasif

3

1 reference

6 August 2017

Miho Yamashita

4

1 reference

6 August 2017

Rodrigo López-Leal

5

1 reference

6 August 2017

Veronica Otero-Corchon

6

1 reference

6 August 2017

Kana Meece

7

1 reference

6 August 2017

Harini Sampath

8

1 reference

6 August 2017

Sharon L Wardlaw

10

1 reference

6 August 2017

Marcelo Rubinstein

11

1 reference

6 August 2017

Malcolm J Low

12

1 reference

6 August 2017

publication date

11 February 2015

1 reference

6 August 2017

1 reference

6 August 2017

volume

11

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6 August 2017

issue

2

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6 August 2017

page(s)

e1004935

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

11 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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Obesity-associated variants within FTO form long-range functional connections with IRX3

9 July 2018

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9 July 2018

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Molecular mechanisms of paralogous compensation and the robustness of cellular networks

9 July 2018

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9 July 2018

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9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

9 July 2018

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9 July 2018

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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

9 July 2018

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9 July 2018

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Lessons from model organisms: phenotypic robustness and missing heritability in complex disease

9 July 2018

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Obesity-programmed mice are rescued by early genetic intervention

9 July 2018

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9 July 2018

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The accessible chromatin landscape of the human genome

9 July 2018

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Genetic redundancies and their evolutionary maintenance

9 July 2018

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9 July 2018

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9 July 2018

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Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy

9 July 2018

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Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons

9 July 2018

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Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo

9 July 2018

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The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2

9 July 2018

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A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells

9 July 2018

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

9 July 2018

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Transcriptional Enhancers in Animal Development and Evolution

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Shadow enhancers foster robustness of Drosophila gastrulation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Phenotypic robustness conferred by apparently redundant transcriptional enhancers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

The adverse effects of obesity on conception and implantation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Turning a hobby into a job: how duplicated genes find new functions

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Impact of male obesity on infertility: a critical review of the current literature

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Shadow enhancers as a source of evolutionary novelty

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis

9 July 2018

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9 July 2018

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9 July 2018

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Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Origin and evolution of circadian clock genes in prokaryotes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Evolution of genetic redundancy.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Canalization: a molecular genetic perspective

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Evolution of transcriptional enhancers and animal diversity.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Metabolic effects of transgenic melanocyte-stimulating hormone overexpression in lean and obese mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

Modular cis-regulatory organization of Endo16, a gut-specific gene of the sea urchin embryo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335486

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004935

Gene Regulation: Enhancers Stepping Out of the Shadow

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25671638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25671638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prenatal ontogenesis of pro-opiomelanocortin in the mouse central nervous system and pituitary gland: an in situ hybridization and immunocytochemical study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25671638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1004935

1 reference

6 August 2017

1 reference

6 August 2017

1 reference