(Q35164669)

6 August 2017

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title

The Hedgehog signaling pathway--implications for drug targets in cancer and neurodegenerative disorders (English)

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6 August 2017

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3

Niels Tommerup

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author name string

Mads Bak

series ordinal

1

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6 August 2017

Claus Hansen

series ordinal

2

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6 August 2017

Lars Allan Larsen

series ordinal

4

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6 August 2017

publication date

1 July 2003

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6 August 2017

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6 August 2017

volume

4

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6 August 2017

issue

4

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6 August 2017

page(s)

411-429

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The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Proteolytic processing yields two secreted forms of sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Autoproteolysis in hedgehog protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Cholesterol modification of hedgehog signaling proteins in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Specification of neuronal fates in the ventral neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Pattern formation: old models out on a limb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The sterol-sensing domain: multiple families, a unique role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog signaling by the patched-smoothened receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Patched acts catalytically to suppress the activity of Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21-->q31.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Megalin functions as an endocytic sonic hedgehog receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog signaling in animal development: paradigms and principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Physical and functional interactions between Zic and Gli proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Pathways and consequences: Hedgehog signaling in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog participates in craniofacial morphogenesis and is down-regulated by teratogenic doses of retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Homozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The phenotypic spectrum of GLI3 morphopathies includes autosomal dominant preaxial polydactyly type-IV and postaxial polydactyly type-A/B; No phenotype prediction from the position of GLI3 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Complications of the naevoid basal cell carcinoma syndrome: results of a population based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Nevoid basal cell carcinoma syndrome. Clinical findings in 37 Italian affected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in SUFU predispose to medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Activation of expression of hedgehog target genes in basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Basal cell carcinoma development is associated with induction of the expression of the transcription factor Gli-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Prediction of central nervous system embryonal tumour outcome based on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Basal cell carcinomas in mice overexpressing Gli2 in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Basal cell carcinomas in mice overexpressing sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Is human patched the gatekeeper of common skin cancers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Unbalanced overexpression of the mutant allele in murine Patched mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog acts as a somatic stem cell factor in the Drosophila ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The Hedgehog and Wnt signalling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Cyclopamine and related steroidal alkaloid teratogens: their occurrence, structural relationship, and biologic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Roughing up Smoothened: chemical modulators of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Introduction of wild-type patched gene suppresses the oncogenic potential of human squamous cell carcinoma cell lines including A431.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Pathophysiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Persephin, a novel neurotrophic factor related to GDNF and neurturin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Behavioural and immunohistochemical changes following supranigral administration of sonic hedgehog in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Perineurium inflammation and altered connexin isoform expression in a rat model of diabetes related peripheral neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Schwann cell-derived desert hedgehog signals nerve sheath formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Shaping morphogen gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Argosomes: a potential vehicle for the spread of morphogens through epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The extracellular matrix in multiple sclerosis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Mutations in the human sterol delta7-reductase gene at 11q12-13 cause Smith-Lemli-Opitz syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Smith-Lemli-Opitz syndrome is caused by mutations in the 7-dehydrocholesterol reductase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The patched signaling pathway in tumorigenesis and development: lessons from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The spectrum of patched mutations in a collection of Australian basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

PTCH gene mutations in odontogenic keratocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

PTCH mutations in squamous cell carcinoma of the skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

PTCH gene mutations in invasive transitional cell carcinoma of the bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The patched polymorphism Pro1315Leu (C3944T) may modulate the association between use of oral contraceptives and breast cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2FPHGS.4.4.411.22751

10.1517/PHGS.4.4.411.22751

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference