(Q35165755)

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PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway

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scholarly article

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Europe PubMed Central

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6 August 2017

PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway (English)

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6 August 2017

author name string

Youcheng Lin

1

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6 August 2017

Zhao Yang

2

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6 August 2017

Abai Xu

3

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6 August 2017

Pei Dong

4

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6 August 2017

Yi Huang

5

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6 August 2017

Huan Liu

6

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6 August 2017

Feida Li

7

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6 August 2017

Haifeng Wang

8

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6 August 2017

Qian Xu

9

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6 August 2017

Yongqiang Wang

10

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6 August 2017

Da Sun

11

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6 August 2017

Yong Zou

12

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6 August 2017

Xiaowen Zou

13

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6 August 2017

Yu Wang

14

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6 August 2017

Duo Zhang

15

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6 August 2017

Hongjie Liu

16

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6 August 2017

Xun Wu

17

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6 August 2017

Meng Zhang

18

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6 August 2017

Yu Fu

19

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6 August 2017

Zhiming Cai

20

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6 August 2017

Chunxiao Liu

21

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6 August 2017

Song Wu

22

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6 August 2017

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publication date

11 March 2015

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6 August 2017

Scientific Reports

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6 August 2017

5

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6 August 2017

8997

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6 August 2017

copyright license

Creative Commons Attribution 4.0 International

11 March 2015

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April 2022 Public Data File from Crossref

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PI3K and cancer: lessons, challenges and opportunities

1 reference

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13 July 2018

Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinoma

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PIK3R1 underexpression is an independent prognostic marker in breast cancer

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N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties

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13 July 2018

Comprehensive molecular characterization of clear cell renal cell carcinoma

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13 July 2018

Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.

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Selenate induces epithelial-mesenchymal transition in a colorectal carcinoma cell line by AKT activation

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13 July 2018

CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.

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PKB/Akt-dependent regulation of cell motility

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Epigenetic alterations involved in cancer stem cell reprogramming

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The evolving concept of cancer and metastasis stem cells

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13 July 2018

Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer

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Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?

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13 July 2018

Cancer cells cyclically lose and regain drug-resistant highly tumorigenic features characteristic of a cancer stem-like phenotype

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13 July 2018

PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer

1 reference

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The cancer stem cell: premises, promises and challenges

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13 July 2018

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

1 reference

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13 July 2018

Vimentin is a novel AKT1 target mediating motility and invasion

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13 July 2018

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

1 reference

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Current management of advanced and metastatic renal cell carcinoma.

1 reference

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13 July 2018

Control of actin filament treadmilling in cell motility

1 reference

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Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation

1 reference

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Epithelial-mesenchymal transitions in development and disease

1 reference

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Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors

1 reference

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The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

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PI3K pathway alterations in cancer: variations on a theme

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The epithelial-mesenchymal transition generates cells with properties of stem cells

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Association between phosphatidylinositol 3-kinase regulatory subunit p85alpha Met326Ile genetic polymorphism and colon cancer risk

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The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

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Renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSREP08997

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Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

1 reference

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21 January 2018

Identifiers

10.1038/SREP08997

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Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

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Europe PubMed Central

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6 August 2017

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