(Q35563032)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP (English)

1 reference

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1 March 2020

5

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1 March 2020

author name string

Michael S Chimenti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Stacie L Bulfer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

R Jeffrey Neitz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Adam R Renslo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Thomas L James

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Michelle R Arkin

7

1 reference

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1 March 2020

Mark J S Kelly

8

1 reference

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1 March 2020

publication date

17 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

1 March 2020

published in

1 reference

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1 March 2020

volume

20

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1 March 2020

issue

6

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1 March 2020

page(s)

788-800

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690569%20AND%20SRC:MED&resulttype=core&format=json

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

1 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057115570550

Recent advances in p97/VCP/Cdc48 cellular functions

21 January 2018

1 reference

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Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy

21 January 2018

1 reference

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ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity

21 January 2018

1 reference

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Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115570550

Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115570550

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

21 January 2018

1 reference

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Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115570550

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

21 January 2018

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Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system

21 January 2018

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The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.

21 January 2018

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ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain

21 January 2018

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Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.

21 January 2018

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Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission

21 January 2018

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Binding-site assessment by virtual fragment screening

21 January 2018

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Medicinal chemistry inspired fragment-based drug discovery

21 January 2018

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Perspectives on NMR in drug discovery: a technique comes of age

21 January 2018

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From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance

21 January 2018

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Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

21 January 2018

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21 January 2018

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Identifying and characterizing binding sites and assessing druggability

21 January 2018

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Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

21 January 2018

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New developments in isotope labeling strategies for protein solution NMR spectroscopy

21 January 2018

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A new labeling method for methyl transverse relaxation-optimized spectroscopy NMR spectra of alanine residues

21 January 2018

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Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy.

21 January 2018

1 reference

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Quantifying Correlations Between Allosteric Sites in Thermodynamic Ensembles

21 January 2018

1 reference

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