(Q35596997)

English

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease

scientific article published on 8 September 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

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Europe PubMed Central

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease (English)

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Europe PubMed Central

PubMed publication ID

9 August 2017

Alzheimer's disease

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neurotransmitter

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based on heuristic

inferred from title

3

object named as

Jill Wegrzyn

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Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Vivian Hook

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Lydiane Funkelstein

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Steven Bark

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mark Kindy

5

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Europe PubMed Central

PubMed publication ID

9 August 2017

Gregory Hook

6

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Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

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publication date

8 September 2011

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Europe PubMed Central

PubMed publication ID

9 August 2017

number of pages

16

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based on heuristic

inferred from page(s)

Biochimica et Biophysica Acta

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Europe PubMed Central

PubMed publication ID

9 August 2017

1824

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Europe PubMed Central

PubMed publication ID

9 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

89-104

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

12 July 2018

Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides

1 reference

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12 July 2018

Reprint of: Catestatin: a multifunctional peptide from chromogranin A.

1 reference

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Specialized roles for cysteine cathepsins in health and disease.

1 reference

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Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication

1 reference

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Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease

1 reference

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Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

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Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses

1 reference

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Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis

1 reference

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12 July 2018

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.

1 reference

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12 July 2018

Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

1 reference

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12 July 2018

Cathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptides

1 reference

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12 July 2018

Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, alpha-MSH, and beta-endorphin

1 reference

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Proteomics of regulated secretory organelles

1 reference

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Cathepsins B and L differentially regulate amyloid precursor protein processing

1 reference

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Isoaspartate-containing amyloid precursor protein-derived peptides alter efficacy and specificity of potential beta-secretases

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Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation

1 reference

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12 July 2018

Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression

1 reference

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Role of cysteine cathepsins in matrix degradation and cell signalling

1 reference

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12 July 2018

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

1 reference

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Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

1 reference

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Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo

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Gamma-secretase: structure, function, and modulation for Alzheimer's disease

1 reference

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12 July 2018

Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein

1 reference

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Proteases for processing proneuropeptides into peptide neurotransmitters and hormones

1 reference

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The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6

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Dynorphin and the pathophysiology of drug addiction

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12 July 2018

Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics

1 reference

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Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease

1 reference

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Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

1 reference

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12 July 2018

Alzheimer's disease

1 reference

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Mapping of the active site of proteases in the 1960s and rational design of inhibitors/drugs in the 1990s

1 reference

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Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

1 reference

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Extracellular proteases in atherosclerosis and restenosis.

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Biosynthesis and alternate targeting of the lysosomal cysteine protease cathepsin L.

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Targeting Rab GTPases to distinct membrane compartments

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Human RAS superfamily proteins and related GTPases

1 reference

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12 July 2018

Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones

1 reference

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12 July 2018

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

1 reference

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12 July 2018

Electron histochemical localization of cathepsin L in the liver

1 reference

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12 July 2018

Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease

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SNARE Protein Structure and Function

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Does my mouse have Alzheimer's disease?

1 reference

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12 July 2018

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

1 reference

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Obliteration of alpha-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice

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Historical review: Opioid receptors

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Processing and activation of lysosomal proteinases

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12 July 2018

Precursor convertases in the secretory pathway, cytosol and extracellular milieu

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

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12 July 2018

Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

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12 July 2018

Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles

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12 July 2018

Annexins: from structure to function

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12 July 2018

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

1 reference

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12 July 2018

Alzheimer's disease: genes, proteins, and therapy

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Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease.

1 reference

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12 July 2018

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

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12 July 2018

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

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12 July 2018

The role of NPY in metabolic homeostasis: implications for obesity therapy

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12 July 2018

Genetically altered transgenic models of Alzheimer's disease.

1 reference

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12 July 2018

Molecular mechanisms and regulation of opioid receptor signaling

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12 July 2018

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

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12 July 2018

Role of hypothalamic neuropeptide Y in feeding and obesity

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12 July 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

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12 July 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

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12 July 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

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12 July 2018

Alzheimer's disease: perspectives for the new millennium

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12 July 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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12 July 2018

The proprotein convertases

1 reference

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12 July 2018

Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons

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12 July 2018

In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells

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12 July 2018

Subtilisin-related serine proteases in the mammalian constitutive secretory pathway

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12 July 2018

Mutant genes in familial Alzheimer's disease and transgenic models

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12 July 2018

Gene regulation and extracellular functions of procathepsin L.

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12 July 2018

Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway

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12 July 2018

Caspases: killer proteases

1 reference

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12 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 July 2018

Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells

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12 July 2018

Cysteine proteinases in GH4C1 cells, a rat pituitary tumor cell line, are secreted by the constitutive and regulated secretory pathways

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12 July 2018

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

12 July 2018

"Prohormone thiol protease" (PTP) processing of recombinant proenkephalin

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12 July 2018

Regulation of the adrenal medulla

1 reference

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12 July 2018

On the size of the active site in proteases. I. Papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

12 July 2018

Carboxypeptidase E

1 reference

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12 July 2018

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12 July 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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12 July 2018

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

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12 July 2018

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12 July 2018

Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer's disease.

1 reference

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26 September 2018

Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Proteomics of neuroendocrine secretory vesicles reveal distinct functional systems for biosynthesis and exocytosis of peptide hormones and neurotransmitters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Cholecystokinin levels in prohormone convertase 2 knock-out mouse brain regions reveal a complex phenotype of region-specific alterations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Role of H+-ATPase-mediated acidification in sorting and release of the regulated secretory protein chromogranin A: evidence for a vesiculogenic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Genetic inactivation of prohormone convertase (PC1) causes a reduction in cholecystokinin (CCK) levels in the hippocampus, amygdala, pons and medulla in mouse brain that correlates with the degree of colocalization of PC1 and CCK mRNA in these struc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Endogenous opioids: overview and current issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Arginine and lysine aminopeptidase activities in chromaffin granules of bovine adrenal medulla: relevance to prohormone processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Full-length and truncated Alzheimer amyloid precursors in chromaffin granules: solubilization of membrane amyloid precursor is mediated by an enzymatic mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232284

26 September 2018

Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CA074 methyl ester: a proinhibitor for intracellular cathepsin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of cathepsin L in rat kidney revealed by immunoenzyme and immunogold techniques

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative proteomics analysis of the secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organellar proteomics: analysis of pancreatic zymogen granule membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallization and preliminary X-ray study of the cathepsin B complexed with CA074, a selective inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the active site of proteases. 3. Mapping the active site of papain; specific peptide inhibitors of papain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unique cleavage specificity of 'prohormone thiol protease' related to proenkephalin processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronociceptive actions of dynorphin maintain chronic neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21925292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBAPAP.2011.08.015

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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