(Q35610303)

9 August 2017

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title

Clinical trials of adenoviruses in brain tumors: a review of Ad-p53 and oncolytic adenoviruses (English)

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9 August 2017

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Giacomo G Vecil

1

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PubMed ID

14682374

9 August 2017

Frederick F Lang

series ordinal

2

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9 August 2017

1 December 2003

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Journal of Neuro-Oncology

9 August 2017

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9 August 2017

65

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9 August 2017

3

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9 August 2017

237-246

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https://scigraph.springernature.com/pub.10.1023/b:neon.0000003653.45635.32

9 August 2017

0 references

cites work

Newcastle disease virus therapy of human tumor xenografts: antitumor effects of local or systemic administration

1 reference

12 December 2020

Replicative adenoviruses for cancer therapy

1 reference

12 December 2020

Clinical evaluation of adenoviral-mediated p53 gene transfer: review of INGN 201 studies

1 reference

12 December 2020

Antitumor effect of vaccinia virus in glioma model

1 reference

12 December 2020

Therapy of peritoneal carcinomatosis from colon cancer with oncolytic adenoviruses

1 reference

12 December 2020

Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency.

1 reference

12 December 2020

Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.

1 reference

12 December 2020

Intracerebral adenovirus-mediated p53 tumor suppressor gene therapy for experimental human glioma.

1 reference

12 December 2020

Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells

1 reference

12 December 2020

In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.

1 reference

12 December 2020

A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer

1 reference

12 December 2020

Epidemiology of brain tumors: the national survey of intracranial neoplasms

1 reference

12 December 2020

Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results

1 reference

12 December 2020

Cancer gene therapy by adenovirus-mediated gene transfer

1 reference

12 December 2020

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

1 reference

12 December 2020

Adenovirus-mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo

1 reference

12 December 2020

Safety evaluation of Ad5CMV-p53 in vitro and in vivo

1 reference

12 December 2020

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

1 reference

12 December 2020

Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers.

1 reference

12 December 2020

A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience).

1 reference

12 December 2020

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

1 reference

12 December 2020

Gene therapy for head and neck cancer. Comparing the tumor suppressor gene p53 and a cell cycle regulator WAF1/CIP1 (p21).

1 reference

12 December 2020

Mutations in the p53 gene occur in diverse human tumour types

1 reference

12 December 2020

Adenovirus-mediated p53 gene therapy for human gliomas

1 reference

12 December 2020

Molecular determinants of cell death induction following adenovirus-mediated gene transfer of wild-type p53 in prostate cancer cells

1 reference

12 December 2020

Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis

1 reference

12 December 2020

Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation

1 reference

12 December 2020

Toward better early-phase brain tumor clinical trials: a reappraisal of current methods and proposals for future strategies.

1 reference

12 December 2020

A genetically engineered influenza A virus with ras-dependent oncolytic properties

1 reference

12 December 2020

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

12 December 2020

Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation

1 reference

12 December 2020

Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity

1 reference

12 December 2020

A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer

1 reference

12 December 2020

Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study

1 reference

12 December 2020

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

1 reference

12 December 2020

Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection

1 reference

12 December 2020

Adenoviral gene therapy

1 reference

12 December 2020

Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer

1 reference

12 December 2020

Update on adenovirus and its vectors

1 reference

12 December 2020

The development of conditionally replicative adenoviruses for cancer therapy.

1 reference

12 December 2020

Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy

1 reference

12 December 2020

Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats.

1 reference

12 December 2020

Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer

1 reference

12 December 2020

Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

1 reference

12 December 2020

Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms.

1 reference

12 December 2020

A phase I/II trial of rAd/p53 (SCH 58500) gene replacement in recurrent ovarian cancer

1 reference

12 December 2020

p53 mutations in human malignant gliomas: comparison of loss of heterozygosity with mutation frequency

1 reference

12 December 2020

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

12 December 2020

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

1 reference

12 December 2020

Human papillomavirus E6E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organotypic cultures of human keratinocytes

1 reference

12 December 2020

The p53 gene and its role in human brain tumors.

1 reference

12 December 2020

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

12 December 2020

Intergeneric poliovirus recombinants for the treatment of malignant glioma

1 reference

12 December 2020

Conditionally replicating herpes vectors for cancer therapy

1 reference

12 December 2020

Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.

1 reference

12 December 2020

Stereotactic histologic correlations of computed tomography- and magnetic resonance imaging-defined abnormalities in patients with glial neoplasms.

1 reference

12 December 2020

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

12 December 2020

Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer

1 reference

12 December 2020

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

1 reference

12 December 2020

Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

1 reference

12 December 2020

Adenoviral-mediated wild-type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation.

1 reference

12 December 2020

Therapy of head and neck squamous cell carcinoma with an oncolytic adenovirus expressing HSV-tk

1 reference

12 December 2020

Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.

1 reference

12 December 2020

p53 Signaling and cell cycle checkpoints

1 reference

12 December 2020

Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene

1 reference

12 December 2020

Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase

1 reference

12 December 2020

Tumors associated with p53 germline mutations: a synopsis of 91 families.

1 reference

12 December 2020

E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors

1 reference

12 December 2020

Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene

1 reference

12 December 2020

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

1 reference

12 December 2020

Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

1 reference

12 December 2020

Adenoviral-mediated gene therapy with Ad5CMVp53 and Ad5CMVp21 in combination with standard therapies in human breast cancer cell lines.

1 reference

12 December 2020

Studies on the use of viruses in the treatment of carcinoma of the cervix

1 reference

12 December 2020

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

1 reference

12 December 2020

Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer

1 reference

12 December 2020

Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma Pathway

1 reference

12 December 2020

1 reference

12 December 2020

Gene therapy of cancer

1 reference

12 December 2020

Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus.

1 reference

12 December 2020

Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma

1 reference

12 December 2020

Cancer gene therapy: fringe or cutting edge?

1 reference

12 December 2020

The presence of the adenovirus E3 region improves the oncolytic potency of conditionally replicative adenoviruses.

1 reference

12 December 2020

Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors

1 reference

12 December 2020

Surfing the p53 network

1 reference

12 December 2020

Leukemia case triggers tighter gene-therapy controls

1 reference

12 December 2020

A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.

1 reference

12 December 2020

Delivery of cell cycle genes to block astrocytoma growth

1 reference

12 December 2020

10.1023/B:NEON.0000003653.45635.32

Identifiers

DOI

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Fatcat

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30 July 2022

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Dimensions Publication ID

1029965524

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Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/3ygqyqmk6bdbziqlleesyrfvfy

30 July 2022

mapped directly with Wikidata item

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https://api.fatcat.wiki/v0/release/3ygqyqmk6bdbziqlleesyrfvfy

30 July 2022