(Q35668617)

9 August 2017

title

Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention (English)

1 reference

9 August 2017

1 reference

5

Roderick H Dashwood

1 reference

9 August 2017

6

Emily Ho

1 reference

9 August 2017

1

Lauren L Atwell

1 reference

9 August 2017

3

Jackilen Shannon

1 reference

9 August 2017

2

Laura M Beaver

1 reference

9 August 2017

David E Williams

4

1 reference

9 August 2017

publication date

1 April 2015

1 reference

Current pharmacology reports

9 August 2017

published in

1 reference

9 August 2017

volume

1

1 reference

9 August 2017

issue

2

1 reference

9 August 2017

page(s)

102-111

1 reference

Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells

9 August 2017

cites work

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27 July 2018

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HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Upregulation of Cyclin B1 by miRNA and its implications in cancer

27 July 2018

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Vegetable and fruit intake after diagnosis and risk of prostate cancer progression

27 July 2018

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Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

27 July 2018

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Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

27 July 2018

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Differential methylation hybridization profiling identifies involvement of STAT1-mediated pathways in breast cancer

27 July 2018

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Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice

27 July 2018

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Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles

27 July 2018

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Signals and combinatorial functions of histone modifications

27 July 2018

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Enforced expression of miR-101 inhibits prostate cancer cell growth by modulating the COX-2 pathway in vivo

27 July 2018

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Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China

27 July 2018

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Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

27 July 2018

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The epigenome as a therapeutic target in prostate cancer

27 July 2018

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Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

27 July 2018

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Detailed analysis of expression and promoter methylation status of apoptosis-related genes in prostate cancer

27 July 2018

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Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver

27 July 2018

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Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells

27 July 2018

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Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice

27 July 2018

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27 July 2018

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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

27 July 2018

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Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells

27 July 2018

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Targeting NRF2 signaling for cancer chemoprevention

27 July 2018

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Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications

27 July 2018

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Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer

27 July 2018

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27 July 2018

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27 July 2018

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Bioavailability and kinetics of sulforaphane in humans after consumption of cooked versus raw broccoli

27 July 2018

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

27 July 2018

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Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate

27 July 2018

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Multi-targeted prevention of cancer by sulforaphane

27 July 2018

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Histone deacetylases and cancer

27 July 2018

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27 July 2018

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Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines

27 July 2018

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Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.

27 July 2018

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Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas.

27 July 2018

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Modest induction of phase 2 enzyme activity in the F-344 rat prostate

27 July 2018

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27 July 2018

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Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo

27 July 2018

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Multiple control of interleukin-8 gene expression

27 July 2018

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27 July 2018

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Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

27 July 2018

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Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.

27 July 2018

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Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

27 July 2018

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Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.

27 July 2018

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Epigenetic modifications in colorectal cancer: molecular insights and therapeutic challenges

25 September 2018

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Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin

25 September 2018

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Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer

25 September 2018

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Organ-specific exposure and response to sulforaphane, a key chemopreventive ingredient in broccoli: implications for cancer prevention.

25 September 2018

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MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals

25 September 2018

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Hallmarks of Cancer: The Next Generation

25 September 2018

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Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

25 September 2018

1 reference

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Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent ki

25 September 2018

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Feeding tomato and broccoli powders enriched with bioactives improves bioactivity markers in rats.

25 September 2018

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Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis

25 September 2018

1 reference

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MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products.

25 September 2018

1 reference

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DNA methylation-dependent epigenetic regulation of gene expression in MCF-7 breast cancer cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450146

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.

25 September 2018

1 reference

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Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.

25 September 2018

1 reference

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Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice

25 September 2018

1 reference

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Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells

25 September 2018

1 reference

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A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.

25 September 2018

1 reference

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Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: role of c-Jun NH2-terminal kinase and histone deacetylase activity

25 September 2018

1 reference

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Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization

25 September 2018

1 reference

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Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization

25 September 2018

1 reference

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Urinary isothiocyanate levels, brassica, and human breast cancer.

25 September 2018

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Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells

25 September 2018

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Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

25 September 2018

1 reference

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Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.

25 September 2018

1 reference

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Brassica vegetables and breast cancer risk

25 September 2018

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Clinical Epigenetics is now a fully open access journal

25 September 2018

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The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells

21 January 2018

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Cancer-protective properties of high-selenium broccoli

1 reference

12 December 2020

Sulforaphane absorption and excretion following ingestion of a semi-purified broccoli powder rich in glucoraphanin and broccoli sprouts in healthy men

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12 December 2020

Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype

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12 December 2020

Brassica vegetable consumption reduces urinary F2-isoprostane levels independent of micronutrient intake

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12 December 2020

Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer

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12 December 2020

Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer

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12 December 2020

GSTP1 promoter hypermethylation is an early event in breast carcinogenesis

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12 December 2020

10.1007/S40495-014-0002-X

Identifiers

DOI

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9 August 2017

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9 August 2017

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