(Q35679564)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis (English)

1 reference

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19 January 2020

8

1 reference

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19 January 2020

Pamela Ohashi

22

1 reference

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19 January 2020

25

Tak W Mak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

5

Jennifer Silvester

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

12

Annick You-Ten

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

10

Jillian Haight

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

1

Zhenyue Hao

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

13

Susan McCracken

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

9

Chiara Gorrini

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

11

Andrew Wakeham

1 reference

19 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

Gordon S Duncan

2

1 reference

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19 January 2020

Yu-Wen Su

3

1 reference

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19 January 2020

Wanda Y Li

4

1 reference

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19 January 2020

Claire Hong

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Han You

7

1 reference

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19 January 2020

Andrew Elia

14

1 reference

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19 January 2020

Qinxi Li

15

1 reference

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19 January 2020

Jacqui Detmar

16

1 reference

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19 January 2020

Andrea Jurisicova

17

1 reference

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19 January 2020

Elias Hobeika

18

1 reference

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19 January 2020

Michael Reth

19

1 reference

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19 January 2020

Yi Sheng

20

1 reference

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19 January 2020

Philipp A Lang

21

1 reference

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19 January 2020

Qing Zhong

23

1 reference

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19 January 2020

Xiaodong Wang

24

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

2 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

19 January 2020

published in

1 reference

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19 January 2020

volume

209

1 reference

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19 January 2020

issue

1

1 reference

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19 January 2020

page(s)

173-186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Posttranslational modification of p53: cooperative integrators of function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Cytoplasmic functions of the tumour suppressor p53.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Tyrosine kinases and their substrates in B lymphocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

A complex barcode underlies the heterogeneous response of p53 to stress

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Mechanism and regulation of class switch recombination

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Vagaries of conditional gene targeting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Testing gene function early in the B cell lineage in mb1-cre mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Antiviral antibody responses: the two extremes of a wide spectrum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

p53 ubiquitination: Mdm2 and beyond

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Immunity by ubiquitylation: a reversible process of modification

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Pathways of apoptosis in lymphocyte development, homeostasis, and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

B-1 cells: the lineage question revisited

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

ATM associates with and phosphorylates p53: mapping the region of interaction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Enhanced phosphorylation of p53 by ATM in response to DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

B cell differentiation and isotype switching is related to division cycle number

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Antiviral immune responses in the absence of organized lymphoid T cell zones in plt/plt mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3260869

25 September 2018

Identifiers

DOI

10.1084/JEM.20111363

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22213803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22213803%20AND%20SRC:MED&resulttype=core&format=json