(Q35774734)

25792665

10 August 2017

title

Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease (English)

1 reference

25792665

chronic obstructive pulmonary disease

10 August 2017

main subject

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Isaac K Sundar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Chad A Lerner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Janice Gerloff

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Ana M Tormos

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Hongwei Yao

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Irfan Rahman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

19 March 2015

1 reference

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

2912-2929

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4478793/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

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12 July 2018

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Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells

12 July 2018

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12 July 2018

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P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence

12 July 2018

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12 July 2018

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Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

12 July 2018

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Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases

12 July 2018

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Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

1 reference

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12 July 2018

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12 July 2018

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Computational classification of mitochondrial shapes reflects stress and redox state

12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

12 July 2018

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Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1

12 July 2018

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12 July 2018

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12 July 2018

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

12 July 2018

1 reference

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12 July 2018

1 reference

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Four faces of cellular senescence.

12 July 2018

1 reference

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12 July 2018

Mechanisms of mitophagy

1 reference

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Establishing primary adult fibroblast cultures from rodents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

p53, ROS and senescence in the control of aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Cigarette smoke induces cellular senescence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

The cyclooxygenase-2-prostaglandin E2 pathway maintains senescence of chronic obstructive pulmonary disease fibroblasts.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Involvement of creatine kinase B in cigarette smoke-induced bronchial epithelial cell senescence.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478793

γ-H2AX foci formation as a pharmacodynamic marker of DNA damage produced by DNA cross-linking agents: results from 2 phase I clinical trials of SJG-136 (SG2000)

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25792665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fibroblast signal transducer and activator of transcription 4 drives cigarette smoke-induced airway fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25792665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1096/FJ.14-268276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792665%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

25792665

1 reference