(Q35800807)

10 August 2017

Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics (English)

1 reference

10 August 2017

0 references

1 reference

5

Daniela Witten

0 references

Oliver Fiehn

12

object named as

Oliver Fiehn

1 reference

10 August 2017

Jessica Tay-Sontheimer

1

1 reference

10 August 2017

Laura M Shireman

2

1 reference

10 August 2017

Richard P Beyer

3

1 reference

10 August 2017

Taurence Senn

4

1 reference

10 August 2017

Robin E Pearce

6

1 reference

10 August 2017

Andrea Gaedigk

7

1 reference

10 August 2017

Cletus L Gana Fomban

8

1 reference

10 August 2017

Justin D Lutz

9

1 reference

10 August 2017

Nina Isoherranen

10

1 reference

10 August 2017

Kenneth E Thummel

11

1 reference

10 August 2017

J Steven Leeder

13

1 reference

10 August 2017

Yvonne S Lin

14

1 reference

10 August 2017

1 December 2014

1 reference

10 August 2017

1 reference

10 August 2017

15

1 reference

10 August 2017

16

1 reference

10 August 2017

1947-1962

1 reference

Fluoxetine- and norfluoxetine-mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19, and CYP3A4

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Complexities of CYP2D6 gene analysis and interpretation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Potential role of CYP2D6 in the central nervous system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

An accelerated workflow for untargeted metabolomics using the METLIN database

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Off-label drug use in pediatric patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Paediatric drug use with focus on off-label prescriptions at Swedish hospitals - a nationwide study

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Developmental pharmacology of tramadol during infancy: ontogeny, pharmacogenetics and elimination clearance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Genomewide association studies and assessment of the risk of disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

11 July 2018

Pediatric dose selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Understanding the relative roles of pharmacogenetics and ontogeny in pediatric drug development and regulatory science.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Variability in drug metabolizing enzyme activity in HIV-infected patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Essentials for starting a pediatric clinical study (1): Pharmacokinetics in children.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

1H NMR metabolomics study of age profiling in children

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Pharmacokinetic predictions in children by using the physiologically based pharmacokinetic modelling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Highly sensitive feature detection for high resolution LC/MS

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

HMDB: a knowledgebase for the human metabolome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Improving pediatric dosing through pediatric initiatives: what we have learned

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

Prediction of drug clearance in children from adults: a comparison of several allometric methods

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486214

The problems in scaling adult drug doses to children.

11 July 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Pinoline may be used as a probe for CYP2D6 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Progesterone oxidation by cytochrome P450 2D isoforms in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Metabolite profiling in human urine by LC-MS/MS: method optimization and application for glucuronides from dextromethorphan metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Developmental changes in human liver CYP2D6 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.155

Pediatric information in drug product labeling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25521354

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25521354

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2217/PGS.14.155

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

25521354

1 reference