(Q35872778)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682034%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor (English)

1 reference

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3 March 2020

author

Christopher J. Schofield

12

1 reference

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3 March 2020

Tobias Krojer

3

1 reference

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3 March 2020

Frank von Delft

9

1 reference

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3 March 2020

Akane Kawamura

11

1 reference

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3 March 2020

13

Paul E Brennan

1 reference

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3 March 2020

author name string

Katherine S England

1

1 reference

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3 March 2020

Anthony Tumber

2

1 reference

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3 March 2020

Giuseppe Scozzafava

4

1 reference

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3 March 2020

Stanley S Ng

5

1 reference

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3 March 2020

Michelle Daniel

6

1 reference

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3 March 2020

Aleksandra Szykowska

7

1 reference

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3 March 2020

KaHing Che

8

1 reference

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3 March 2020

Nicola A Burgess-Brown

10

1 reference

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3 March 2020

publication date

1 December 2014

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3 March 2020

1 reference

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3 March 2020

volume

5

1 reference

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3 March 2020

issue

12

1 reference

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3 March 2020

page(s)

1879-1886

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682034%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

3 March 2020

copyright license

start time

23 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Human UTY(KDM6C) Is a Male-specific N -Methyl Lysyl Demethylase

11 July 2018

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Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

11 July 2018

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KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.

11 July 2018

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Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity

11 July 2018

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A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth

11 July 2018

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Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases

11 July 2018

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Mechanisms of human histone and nucleic acid demethylases

11 July 2018

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

11 July 2018

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Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

11 July 2018

1 reference

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Epigenetic protein families: a new frontier for drug discovery

11 July 2018

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Molecular mechanisms and potential functions of histone demethylases

11 July 2018

1 reference

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Histone methylation: a dynamic mark in health, disease and inheritance

11 July 2018

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A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases

11 July 2018

1 reference

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Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

11 July 2018

1 reference

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Inhibition of 2-oxoglutarate dependent oxygenases

11 July 2018

1 reference

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Structural studies on human 2-oxoglutarate dependent oxygenases

11 July 2018

1 reference

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Development of homogeneous luminescence assays for histone demethylase catalysis and binding.

11 July 2018

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Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

11 July 2018

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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Demethylation of epiregulin gene by histone demethylase FBXL11 and BCL6 corepressor inhibits osteo/dentinogenic differentiation

11 July 2018

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Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1039/C4MD00291A

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682034%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26682034%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

26682034

1 reference