(Q36006932)

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Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

neural stem cell

1 reference

based on heuristic

inferred from title

author name string

Yan Song

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Bingwei Lu

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

3 April 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

number of pages

13

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

11 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

17716-17728

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

NUMB-ing down cancer by more than just a NOTCH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Endocytosis and intracellular trafficking of Notch and its ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The multiple functions of Numb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Numb regulates post-endocytic trafficking and degradation of Notch1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Notch signaling: the core pathway and its posttranslational regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The canonical Notch signaling pathway: unfolding the activation mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Neural stem cells: balancing self-renewal with differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Auxilin is essential for Delta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Tumor suppressors: control of signaling by endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Adaptable adaptors for coated vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Molecular architecture and functional model of the endocytic AP2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Numb is an endocytic protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

Targeting signals and subunit interactions in coated vesicle adaptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

2 October 2017

The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

11 July 2018

Endocytic control of epithelial polarity and proliferation in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

11 July 2018

Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

11 July 2018

Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

11 July 2018

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366835

11 July 2018

Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Regulation of post-embryonic neuroblasts by Drosophila Grainyhead.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Numb3 is an endocytosis adaptor for the inflammatory marker P-selectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch to the dorsoventral boundary during Drosophila wing development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Endocytosis by Numb breaks Notch symmetry at cytokinesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

AP-1 controls the trafficking of Notch and Sanpodo toward E-cadherin junctions in sensory organ precursors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Unequal segregation of Neuralized biases Notch activation during asymmetric cell division

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Notch signal organizes the Drosophila olfactory circuitry by diversifying the sensory neuronal lineages.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Role of Drosophila alpha-adaptin in presynaptic vesicle recycling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.360719

21 January 2018

Identifiers

10.1074/JBC.M112.360719

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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