(Q36217340)

English

Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein (English)

1 reference

Europe PubMed Central

12 August 2017

1 reference

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7

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Hilal A Lashuel

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Europe PubMed Central

12 August 2017

1

object named as

Bruno Fauvet

1 reference

Europe PubMed Central

12 August 2017

4

object named as

Igor Dikiy

1 reference

Europe PubMed Central

12 August 2017

Mohamed-Bilal Fares

2

object named as

Mohamed-Bilal Fares

1 reference

Europe PubMed Central

12 August 2017

author name string

Filsy Samuel

3

1 reference

Europe PubMed Central

12 August 2017

Anurag Tandon

5

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Europe PubMed Central

12 August 2017

David Eliezer

6

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Europe PubMed Central

12 August 2017

language of work or name

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publication date

20 June 2012

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Europe PubMed Central

12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

12 August 2017

287

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Europe PubMed Central

12 August 2017

34

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Europe PubMed Central

12 August 2017

28243-28262

1 reference

Europe PubMed Central

12 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3436566/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

NMR View: A computer program for the visualization and analysis of NMR data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Protein N-terminal acetyltransferases: when the start matters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

A soluble α-synuclein construct forms a dynamic tetramer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method

1 reference

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1 October 2017

Towards a functional understanding of protein N-terminal acetylation

1 reference

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1 October 2017

Targeted amino-terminal acetylation of recombinant proteins in E. coli

1 reference

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1 October 2017

Protein acetylation in archaea, bacteria, and eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Cellular structural biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Phosphorylation of synucleins by members of the Polo-like kinase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster

1 reference

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1 October 2017

Expressed protein ligation: a resourceful tool to study protein structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

The first N-terminal amino acids of alpha-synuclein are essential for alpha-helical structure formation in vitro and membrane binding in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Residual structure, backbone dynamics, and interactions within the synuclein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Interactions between metals and alpha-synuclein--function or artefact?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Cell systems and the toxic mechanism(s) of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Physiological importance and identification of novel targets for the N-terminal acetyltransferase NatB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Ubiquitination of alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

The stress-induced Tfs1p requires NatB-mediated acetylation to inhibit carboxypeptidase Y and to regulate the protein kinase A pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Nanotubular highways for intercellular organelle transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Plasma Membrane Disruption: Repair, Prevention, Adaptation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

The diversity of acetylated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

A method for efficient isotopic labeling of recombinant proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

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1 October 2017

Identification of two distinct synucleins from human brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

Requirement of amino-terminal modification for striated muscle alpha-tropomyosin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

The role of the alpha-helix dipole in protein function and structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

1 October 2017

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

29 June 2018

N-Terminal acetylation is critical for forming α-helical oligomer of α-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

29 June 2018

The acetylation state of human fetal hemoglobin modulates the strength of its subunit interactions: long-range effects and implications for histone interactions in the nucleosome

1 reference

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29 June 2018

A cleavage cocktail for methionine-containing peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

29 June 2018

Lipid composition of synaptic plasma membranes isolated from rat brain by zonal centrifugation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

29 June 2018

MAK3 encodes an N-acetyltransferase whose modification of the L-A gag NH2 terminus is necessary for virus particle assembly

1 reference

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29 June 2018

A comparison of the turnover of alpha-N-acetylated and nonacetylated mouse L-cell proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

29 June 2018

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Conformational properties of alpha-synuclein in its free and lipid-associated states

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Co- and post-translational modifications of the 26S proteasome in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Fatty acid composition of human brain phospholipids during normal development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436566

22 September 2018

Structures of N-terminally acetylated proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

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https://api.crossref.org/works/10.1074%2FJBC.M112.383711

21 January 2018

Evidence that approximately eighty per cent of the soluble proteins from Ehrlich ascites cells are Nalpha-acetylated

1 reference

https://pubmed.ncbi.nlm.nih.gov/22718772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In-cell NMR spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22718772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into the mechanism and catalysis of the native chemical ligation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22718772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards elucidation of the role of ubiquitination in the pathogenesis of Parkinson's disease with semisynthetic ubiquitinated α-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22718772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N alpha-acetyltransferase deficiency alters protein synthesis in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22718772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.383711

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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