(Q36297787)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

chronic obstructive pulmonary disease

24 February 2020

main subject

DNA damage

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Graeme Hewitt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

John J Taylor

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Anthony De Soyza

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Joao F Passos

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

10

Maria G Belvisi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Jodie Birch

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Rhys K Anderson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Clara Correia-Melo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Francisco Madeira Marques

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Nicola J Green

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Elizabeth Moisey

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Mark A Birrell

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Fiona Black

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Andrew J Fisher

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

publication date

18 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

24 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

10

1 reference

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24 February 2020

page(s)

L1124-37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

Smoking accelerates aging of the small airway epithelium

24 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Five dysfunctional telomeres predict onset of senescence in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere length is a determinant of emphysema susceptibility.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Systematic review with meta-analysis of the epidemiological evidence relating smoking to COPD, chronic bronchitis and emphysema

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

The pathology of chronic obstructive pulmonary disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Chemokine signaling via the CXCR2 receptor reinforces senescence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

A continuous correlation between oxidative stress and telomere shortening in fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Cellular senescence: when bad things happen to good cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Cigarette smoke induces cellular senescence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Lung fibroblasts from patients with emphysema show markers of senescence in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Shelterin: the protein complex that shapes and safeguards human telomeres

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Ink4a/Arf expression is a biomarker of aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

A DNA damage checkpoint response in telomere-initiated senescence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Physiological changes in respiratory function associated with ageing.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Mammalian telomeres end in a large duplex loop

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

DNA damage as a molecular link in the pathogenesis of COPD in smokers.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere shortening in chronic obstructive pulmonary disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Cellular senescence in aging primates.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Increased DNA damage in patients with chronic obstructive pulmonary disease who had once smoked or been exposed to biomass

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Immunohistochemical evaluation of oxidative stress in murine lungs after cigarette smoke exposure

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4652155

Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging

22 September 2018

1 reference

12 December 2020

DNA damage in peripheral blood of patients with chronic obstructive pulmonary disease (COPD)

1 reference

12 December 2020

Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease

1 reference

12 December 2020

Alveolar cell senescence in patients with pulmonary emphysema

1 reference

12 December 2020

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

12 December 2020

10.1152/AJPLUNG.00293.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26386121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26386121%20AND%20SRC:MED&resulttype=core&format=json