(Q36539483)

14 August 2017

1 reference

title

The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy (English)

1 reference

14 August 2017

3

Agnes Görlach

1 reference

14 August 2017

Rachida S Bel Aiba

1

1 reference

14 August 2017

Elitsa Y Dimova

series ordinal

2

1 reference

14 August 2017

Thomas Kietzmann

series ordinal

4

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 August 2006

1 reference

Expert Opinion on Therapeutic Targets

14 August 2017

published in

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14 August 2017

volume

10

1 reference

14 August 2017

issue

4

1 reference

14 August 2017

page(s)

583-599

1 reference

Hypoxia-responsive transcription factors.

14 August 2017

cites work

1 reference

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Zonation of parenchymal and nonparenchymal metabolism in liver

21 January 2018

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Oxygen: modulator of metabolic zonation and disease of the liver

21 January 2018

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Oxygen: modulator of physiological and pathophysiological processes in the liver

21 January 2018

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Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF-1 and mechanisms of hypoxia sensing

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The mammalian basic helix-loop-helix/PAS family of transcriptional regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Binding and regulation of hypoxia-inducible factor-1 by the inhibitory PAS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Human HIF-3alpha4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Signal transduction to hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Molecular basis of the VHL hereditary cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF hydroxylation and the mammalian oxygen-sensing pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Sumoylation increases HIF-1alpha stability and its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Cytokines and the regulation of hypoxia-inducible factor (HIF)-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

ERK activation upon hypoxia: involvement in HIF-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Current understanding of HIF in renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Oxidative stress and hypoxia: implications for plasminogen activator inhibitor-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Modulation of glucokinase expression by hypoxia-inducible factor 1 and upstream stimulatory factor 2 in primary rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Identification and characterization of the hypoxia-responsive element of the human placental 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

A role for mitochondrial enzymes in inherited neoplasia and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Causes and consequences of tumour acidity and implications for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Localization and activity of renal carbonic anhydrase (CA) in CA-II deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The carbonic anhydrases: widening perspectives on their evolution, expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Multiple roles of carbonic anhydrase in cellular transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

cDNA cloning and developmental expression of murine carbonic anhydrase-related proteins VIII, X, and XI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor 1 transactivates the human leptin gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transglutaminase 2: an enigmatic enzyme with diverse functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transglutaminases: crosslinking enzymes with pleiotropic functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

A novel function of tissue-type transglutaminase: protein disulphide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transglutaminase 2 in the balance of cell death and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Tissue transglutaminase in normal and abnormal wound healing: review article

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Increase in proliferative markers after inhibition of transglutaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Evidence for participation of transglutaminase in receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Is the hypoxia-inducible factor pathway important in gastric cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor 1alpha in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The HIF pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Knockdown of hypoxia-inducible factor-1alpha in breast carcinoma MCF-7 cells results in reduced tumor growth and increased sensitivity to methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Breast carcinomas fulfill the Warburg hypothesis and provide metabolic markers of cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-inducible factor 1 (HIF-1) in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

New anticancer strategies targeting HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The ubiquitin system: pathogenesis of human diseases and drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia inducible factor-1: a novel target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Development of novel therapeutic strategies that target HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hsp90: chaperoning signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Resveratrol: a molecule whose time has come? And gone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Inhibition of glucose and dehydroascorbic acid uptakes by resveratrol in human transformed myelocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Genistein restricts leptin secretion from rat adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Cobalt induces heme oxygenase-1 expression by a hypoxia-inducible factor-independent mechanism in Chinese hamster ovary cells: regulation by Nrf2 and MafG transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Acute hypoxia increases ornithine decarboxylase activity and polyamine concentrations in fetal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.4.583

10.1517/14728222.10.4.583

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference