(Q36582330)

English

The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach

scientific article published on 8 January 2013

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach (English)

1 reference

Europe PubMed Central

15 August 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

Manon van Engeland

5

object named as

Manon van Engeland

1 reference

Europe PubMed Central

15 August 2017

Piet A van den Brandt

object named as

Piet A van den Brandt

6

0 references

author name string

Matty P Weijenberg

1

1 reference

Europe PubMed Central

15 August 2017

Laura A E Hughes

2

1 reference

Europe PubMed Central

15 August 2017

Martijn J L Bours

3

1 reference

Europe PubMed Central

15 August 2017

Colinda C J M Simons

4

1 reference

Europe PubMed Central

15 August 2017

publication date

8 January 2013

1 reference

Europe PubMed Central

15 August 2017

Current nutrition reports

1 reference

Europe PubMed Central

15 August 2017

2

1 reference

Europe PubMed Central

15 August 2017

1

1 reference

Europe PubMed Central

15 August 2017

19-26

1 reference

Europe PubMed Central

15 August 2017

copyright license

Creative Commons Attribution-NonCommercial 2.0 Generic

8 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1007/s13668-012-0038-7

0 references

Obesity, energy balance, and cancer: new opportunities for prevention

1 reference

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9 September 2017

Lifestyle factors in cancer survivorship

1 reference

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9 September 2017

Sarcopenic obesity: A Critical appraisal of the current evidence.

1 reference

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9 September 2017

The role of obesity in cancer survival and recurrence

1 reference

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9 September 2017

Commentary: Lifestyle factors and colorectal cancer microsatellite instability--molecular pathological epidemiology science, based on unique tumour principle

1 reference

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9 September 2017

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis

1 reference

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9 September 2017

mTOR signaling in growth control and disease

1 reference

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9 September 2017

Lost in translation: regulation of skeletal muscle protein synthesis

1 reference

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9 September 2017

Energy restriction during childhood and early adulthood and ovarian cancer risk

1 reference

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9 September 2017

Multiple signal pathways in obesity-associated cancer

1 reference

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9 September 2017

The role of diet and physical activity in breast, colorectal, and prostate cancer survivorship: a review of the literature

1 reference

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9 September 2017

Consideration of quality of life in cancer survivorship research.

1 reference

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9 September 2017

mTOR signaling in disease

1 reference

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9 September 2017

Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis

1 reference

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9 September 2017

Linking long-term dietary patterns with gut microbial enterotypes

1 reference

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9 September 2017

Body fatness during childhood and adolescence, adult height, and risk of colorectal adenoma in women

1 reference

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9 September 2017

Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk

1 reference

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9 September 2017

Exercise, amino acids, and aging in the control of human muscle protein synthesis.

1 reference

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9 September 2017

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).

1 reference

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9 September 2017

mTOR: from growth signal integration to cancer, diabetes and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

The role of body mass index, physical activity, and diet in colorectal cancer recurrence and survival: a review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Body size and incident colorectal cancer: a prospective study of older women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Targeting mTOR in cancer: renal cell is just a beginning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Energy balance, the PI3K-AKT-mTOR pathway genes, and the risk of bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

SIRT1 negatively regulates the mammalian target of rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Molecular mechanisms in aging and current strategies to counteract sarcopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

A systematic review of the association between physical activity and colorectal cancer risk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

A quantitative analysis of body mass index and colorectal cancer: findings from 56 observational studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Physical activity and colon cancer prevention: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Lifestyle factors and colorectal cancer risk (1): systematic review and meta-analysis of associations with body mass index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Reducing the weight of cancer: mechanistic targets for breaking the obesity-carcinogenesis link

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Sarcopenic obesity: definition, cause and consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

PI3K pathway alterations in cancer: variations on a theme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Occupational physical activity and risk for cancer of the colon and rectum in Sweden among men and women by anatomic subsite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Leisure-time physical activity patterns and risk of colon cancer in women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Obesity and colorectal cancer risk: a meta-analysis of cohort studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Diabetes mellitus and risk of colorectal cancer: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Childhood growth and adult cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Insulin, insulin-like growth factors and colon cancer: a review of the evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

Energy balance and cancer: the role of insulin and insulin-like growth factor-I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

The role of calories and caloric restriction in carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

9 September 2017

The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Energy restriction early in life and colon carcinoma risk: results of The Netherlands Cohort Study after 7.3 years of follow-up

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Diet in adolescence and the risk of breast cancer: results of the Netherlands Cohort Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Colorectal cancer: the role of dietary fat and caloric restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Influence of caloric intake on experimental carcinogenesis: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

30 September 2017

Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Dietary energy balance modulation of epithelial carcinogenesis: a role for IGF-1 receptor signaling and crosstalk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Occupational and recreational physical activity during adult life and the risk of cancer among men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Anthropometric factors in adulthood and risk of colorectal adenomas: The French E3N-EPIC prospective cohort.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Age dependence of radiation-induced renal cell carcinomas in an Eker rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

mTOR-what does it do?

1 reference

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20 September 2018

A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence

1 reference

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20 September 2018

Early life events and later risk of colorectal cancer: age-period-cohort modelling in the Nordic countries and Estonia.

1 reference

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20 September 2018

Breast cancer risk after caloric restriction during the 1944-1945 Dutch famine.

1 reference

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20 September 2018

Energy restriction in childhood and adolescence and risk of prostate cancer: results from the Netherlands Cohort Study.

1 reference

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20 September 2018

Energy balance and colon cancer--beyond physical activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3562550

20 September 2018

Obesity and cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13668-012-0038-7

21 January 2018

Trends in colorectal cancer incidence in Norway by gender and anatomic site: an age–period–cohort analysis

1 reference

https://api.crossref.org/works/10.1007%2FS13668-012-0038-7

21 January 2018

Recreational physical activity and cancer risk in subsites of the colon (the Nord-Trøndelag Health Study)

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design considerations for genomic association studies: importance of gene-environment interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23396869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13668-012-0038-7

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

ResearchGate publication ID

0 references

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