(Q36843682)

English

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

scientific article published on 23 June 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

16 August 2017

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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Coagulation factor VIII

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3

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Bruce R Blazar

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

6

object named as

Hans D Ochs

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Gordon J. Freeman

4

object named as

Gordon J Freeman

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Baowei Peng

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Peiqing Ye

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

David J Rawlings

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Carol H Miao

7

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Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

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publication date

23 June 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

112

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1662-1672

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Recent advances in immune modulation

1 reference

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Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice

1 reference

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The B7 family revisited

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Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins

1 reference

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Induction of B7-1 in podocytes is associated with nephrotic syndrome

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An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells

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Immune implications of gene therapy for hemophilia

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Phase 1 trial of FVIII gene transfer for severe hemophilia A using a retroviral construct administered by peripheral intravenous infusion

1 reference

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Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer

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Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

1 reference

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Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling

1 reference

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ICOS is essential for effective T-helper-cell responses

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ICOS is critical for CD40-mediated antibody class switching

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ICOS co-stimulatory receptor is essential for T-cell activation and function

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B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production

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Induction, binding specificity and function of human ICOS

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

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Sustained expression of human factor VIII in mice using a parvovirus-based vector.

1 reference

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T-cell co-stimulation through B7RP-1 and ICOS

1 reference

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Animal testing of retroviral-mediated gene therapy for factor VIII deficiency

1 reference

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Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice

1 reference

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

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CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

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In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs

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Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer

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Immune deviation by mucosal antigen administration suppresses gene-transfer-induced inhibitor formation to factor IX.

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Proceedings: A more uniform measurement of factor VIII inhibitors

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Regulation of immune and autoimmune responses by ICOS.

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1 reference

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1 reference

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Prevention and treatment of factor VIII inhibitors in murine hemophilia A.

1 reference

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Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the immune response to human factor VIII in murine hemophilia A

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of collagen-induced arthritis by blockade of inducible costimulator-B7 homologous protein costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy in hemophilia: clinical trials update

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ICOS molecule plays a crucial role in the development of mucosal tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy for the hemophilias

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune dysfunction associated with graft-versus-host reaction in mice transplanted across minor histocompatibility barriers. I. Depressed antigen-specific antibody responses to bacteriophage phi chi 174

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2008-01-128413

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

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