(Q36870363)

16 August 2017

1 reference

title

Links between metabolism and apoptosis in mammalian cells: applications for anti-apoptosis engineering (English)

1 reference

16 August 2017

1 reference

2

Michael J Betenbaugh

1 reference

16 August 2017

Brian S Majors

1

1 reference

16 August 2017

Gisela G Chiang

series ordinal

3

1 reference

16 August 2017

language of work or name

1 reference

23 May 2007

1 reference

16 August 2017

published in

Metabolic Engineering

1 reference

16 August 2017

volume

9

1 reference

16 August 2017

issue

4

1 reference

16 August 2017

page(s)

317-326

1 reference

Apoptosis in cell culture

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Chemical caspase inhibitors enhance cell culture viabilities and protein titer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Life and death in mammalian cell culture: strategies for apoptosis inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Fortification of a protein-free cell culture medium with plant peptones improves cultivation and productivity of an interferon-gamma-producing CHO cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Prolongation of murine hybridoma cell survival in stationary batch culture by Bcl-xL expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-x(L) mediates increased production of humanized monoclonal antibodies in Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The Bcl2 family: regulators of the cellular life-or-death switch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondria and calcium: from cell signalling to cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Apoptosis in batch cultures of Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Role of oxidative phosphorylation in Bax toxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The mitochondrial permeability transition pore complex as a pharmacological target. An introduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Low-glutamine fed-batch cultures of 293-HEK serum-free suspension cells for adenovirus production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mammalian Bax triggers apoptotic changes in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

GLUT-1 reduces hypoxia-induced apoptosis and JNK pathway activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Overcoming apoptosis: new methods for improving protein-expression systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Glucose transport and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Genetically engineering mammalian cell lines for increased viability and productivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-2 regulation of mitochondrial energetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondrial ca(2+) signaling and cardiac apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Hexokinase II: the integration of energy metabolism and control of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondrial Ca2+ homeostasis in intact cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondria as all-round players of the calcium game

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Regulation of glucose metabolism in the lung: Hexokinase-catalyzed phosphorylation, a rate-limiting step

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Study of caspase inhibitors for limiting death in mammalian cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Regulation of death receptor-mediated apoptosis pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Modulation of cell death in yeast by the Bcl-2 family of proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

VDAC regulation by the Bcl-2 family of proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Role of the mitochondrial membrane permeability transition in cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Mitochondrial membrane permeability transition and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Glucokinase expression in rat hepatoma cells induces glucose uptake and is rate limiting in glucose utilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Growth factors can influence cell growth and survival through effects on glucose metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Metabolic engineering of apoptosis in cultured animal cells: implications for the biotechnology industry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Movement of Bax from the cytosol to mitochondria during apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Transcriptional profiling of apoptotic pathways in batch and fed-batch CHO cell cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Development of Animal-free, Protein-Free and Chemically-Defined Media for NS0 Cell Culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

Regulation of sodium-calcium exchange and mitochondrial energetics by Bcl-2 in the heart of transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2007.05.003

10.1016/J.YMBEN.2007.05.003

7 January 2021

Identifiers

DOI

1 reference

16 August 2017

1 reference