(Q36918695)

17 August 2017

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title

Strategies that modulate inflammasomes: insights from host-pathogen interactions (English)

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17 August 2017

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3

Grant McFadden

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17 August 2017

James B Johnston

1

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17 August 2017

Masmudur M Rahman

series ordinal

2

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17 August 2017

publication date

24 August 2007

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Seminars in Immunopathology

17 August 2017

published in

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17 August 2017

volume

29

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17 August 2017

issue

3

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17 August 2017

page(s)

261-274

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Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions

17 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

Antiviral signaling through pattern recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

Secreted immunomodulatory viral proteins as novel biotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-007-0080-5

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

21 January 2018

1 reference

12 December 2020

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

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12 December 2020

Familial autoinflammatory diseases: genetics, pathogenesis and treatment

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12 December 2020

New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

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12 December 2020

TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers

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12 December 2020

NF-kappaB signaling: pros and cons of altering NF-kappaB as a therapeutic approach

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12 December 2020

Innate immune recognition

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12 December 2020

Comparative analysis of apoptosis and inflammation genes of mice and humans

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12 December 2020

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

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12 December 2020

Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.

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12 December 2020

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

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12 December 2020

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12 December 2020

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

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12 December 2020

The role of the purinergic P2X7 receptor in inflammation

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12 December 2020

Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

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12 December 2020

The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

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12 December 2020

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

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12 December 2020

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12 December 2020

Signalling pathways and molecular interactions of NOD1 and NOD2

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12 December 2020

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

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12 December 2020

IL-12 and IL-18 act in synergy to clear vaccinia virus infection: involvement of innate and adaptive components of the immune system

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12 December 2020

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

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12 December 2020

Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domain

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12 December 2020

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

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12 December 2020

Toll like receptors and viruses.

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12 December 2020

Orthopoxvirus IL-18 binding proteins: affinities and antagonist activities

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12 December 2020

The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model

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12 December 2020

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition

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12 December 2020

Gout-associated uric acid crystals activate the NALP3 inflammasome

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12 December 2020

The danger model: a renewed sense of self

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12 December 2020

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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12 December 2020

Identification and characterization of a novel bacterial virulence factor that shares homology with mammalian Toll/interleukin-1 receptor family proteins

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12 December 2020

Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatal-onset multisystem inflammatory disease

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12 December 2020

The tip of a molecular syringe

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12 December 2020

Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression

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12 December 2020

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

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12 December 2020

Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta

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12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12 December 2020

The PYRIN domain: a member of the death domain-fold superfamily

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12 December 2020

Type I interferons (alpha/beta) in immunity and autoimmunity

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12 December 2020

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

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12 December 2020

A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection

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12 December 2020

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

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12 December 2020

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

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12 December 2020

The innate antiviral response: new insights into a continuing story

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12 December 2020

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

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12 December 2020

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

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12 December 2020

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

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12 December 2020

Biologic basis for interleukin-1 in disease

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12 December 2020

Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway.

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12 December 2020

Human Nod1 confers responsiveness to bacterial lipopolysaccharides

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12 December 2020

Hereditary periodic fever syndromes

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12 December 2020

Toll-like receptors in innate immunity

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12 December 2020

Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme

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12 December 2020

Therapeutic targets in inflammatory disease

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12 December 2020

Putting E. coli on a pedestal: a unique system to study signal transduction and the actin cytoskeleton

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12 December 2020

Triggering the interferon antiviral response through an IKK-related pathway

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12 December 2020

Altered cytokine production in mice lacking P2X(7) receptors

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12 December 2020

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

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12 December 2020

Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB

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12 December 2020

ICEBERG: a novel inhibitor of interleukin-1beta generation

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12 December 2020

Pathogen recognition and innate immunity

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12 December 2020

NACHT-LRR proteins (NLRs) in bacterial infection and immunity

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12 December 2020

Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

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12 December 2020

The inflammasome: first line of the immune response to cell stress

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12 December 2020

Irreversible inhibitors of serine, cysteine, and threonine proteases

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12 December 2020

Campylobacter jejuni infection of differentiated THP-1 macrophages results in interleukin 1 beta release and caspase-1-independent apoptosis

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12 December 2020

Macrophages in rheumatoid arthritis

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12 December 2020

Interleukin-18 improves the early defence system against influenza virus infection by augmenting natural killer cell-mediated cytotoxicity

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12 December 2020

Inflammatory caspases and inflammasomes: master switches of inflammation

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12 December 2020

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

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12 December 2020

NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer.

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12 December 2020

Translational mini-review series on Toll-like receptors: recent advances in understanding the role of Toll-like receptors in anti-viral immunity

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12 December 2020

Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release

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12 December 2020

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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12 December 2020

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

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12 December 2020

Dual role of inflammatory stimuli in activation-induced cell death of mouse microglial cells. Initiation of two separate apoptotic pathways via induction of interferon regulatory factor-1 and caspase-11.

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12 December 2020

Cryopyrin activates the inflammasome in response to toxins and ATP

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12 December 2020

Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation

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12 December 2020

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

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12 December 2020

The inflammasome--a linebacker of innate defense.

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12 December 2020

The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells

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12 December 2020

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

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12 December 2020

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

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12 December 2020

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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12 December 2020

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

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12 December 2020

NLRs join TLRs as innate sensors of pathogens

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12 December 2020

Poxviruses and immune evasion

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12 December 2020

Viral recognition by Toll-like receptors

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12 December 2020

Toll-like receptor signalling

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12 December 2020

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

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12 December 2020

ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules

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12 December 2020

Extensive gene gain associated with adaptive evolution of poxviruses

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12 December 2020

Dissociation of IL-1 beta synthesis and secretion in human blood monocytes stimulated with bacterial cell wall products

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12 December 2020

Molecular identification of a danger signal that alerts the immune system to dying cells

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12 December 2020

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

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12 December 2020

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

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12 December 2020

Caspase-1 activation by Salmonella

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12 December 2020

The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations

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12 December 2020

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

1 reference

12 December 2020

Inhibitors of TACE and Caspase-1 as anti-inflammatory drugs

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12 December 2020

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

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12 December 2020

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

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12 December 2020

CATERPILLERs, pyrin and hereditary immunological disorders

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12 December 2020

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

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12 December 2020

Endotoxin-stimulated monocytes release multiple forms of IL-1 beta, including a proIL-1 beta form whose detection is affected by export

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12 December 2020

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12 December 2020

Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

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12 December 2020

Intracellular pattern recognition receptors in the host response

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12 December 2020

Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation

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12 December 2020

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

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12 December 2020

Virus encoded cytokines and cytokine receptors

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12 December 2020

Cryopyrin: In from the Cold

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12 December 2020

Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

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12 December 2020

10.1007/S00281-007-0080-5

Identifiers

DOI

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17 August 2017

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