(Q36949688)

English

Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors

scientific article published on 20 August 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

object named as

Ann Vos

10

0 references

object named as

Dirk Jochmans

12

0 references

object named as

Kurt Vermeire

13

0 references

Dominique Schols

object named as

Dominique Schols

14

0 references

author name string

Olivia Goethals

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Reginald Clayton

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Marcia Van Ginderen

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Inge Vereycken

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Elisabeth Wagemans

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Peggy Geluykens

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Koen Dockx

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Rudy Strijbos

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Veerle Smits

9

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Geert Meersseman

11

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Sabine Hallenberger

15

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Kurt Hertogs

16

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

20 August 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

82

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

10366-10374

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Raltegravir (MK-0518): a novel integrase inhibitor for the treatment of HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

HIV-1 integrase inhibitors: 2005-2006 update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Design of second generation HIV-1 integrase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Novel HIV-1 integrase inhibitors derived from quinolone antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Integrase inhibitors to treat HIV/AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Novel inhibitors of HIV-1 integration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

S-1360 Shionogi-GlaxoSmithKline.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Inhibition of human immunodeficiency virus type 1 isolates by the integrase inhibitor L-731,988, a diketo Acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

HIV integrase structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Molecular mechanisms in retrovirus DNA integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Integration is essential for efficient gene expression of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

29 September 2017

TMC125 displays a high genetic barrier to the development of resistance: evidence from in vitro selection experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

27 June 2018

Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

4 September 2018

Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

4 September 2018

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

4 September 2018

Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

4 September 2018

Similarities between initiation of V(D)J recombination and retroviral integration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573211

4 September 2018

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral activity, pharmacokinetics, and dose response of the HIV-1 integrase inhibitor GS-9137 (JTK-303) in treatment-naive and treatment-experienced patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel HIV integrase inhibitors with anti-HIV activity: insights into integrase inhibition from docking studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raltegravir: a new antiretroviral class for salvage therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV Drug Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18715920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00470-08

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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