(Q36973492)

17 August 2017

1 reference

title

The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases (English)

1 reference

17 August 2017

1 reference

Andrea Contestabile

3

0 references

Elisabetta Ciani

object named as

Elisabetta Ciani

series ordinal

2

0 references

author name string

Antonio Contestabile

series ordinal

1

1 reference

17 August 2017

publication date

17 October 2007

1 reference

17 August 2017

published in

Neurochemical Research

1 reference

17 August 2017

volume

33

1 reference

17 August 2017

issue

2

1 reference

17 August 2017

page(s)

318-327

1 reference

The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease.

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

E4 allele dosage does not predict cholinergic activity or synapse loss in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

The cholinergic deficit coincides with Abeta deposition at the earliest histopathologic stages of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9497-4

Increased anticholinergic challenge-induced memory impairment associated with the APOE-epsilon4 allele in the elderly: a controlled pilot study

21 January 2018

1 reference

12 December 2020

Preliminary characterization of the central nervous system in partial trisomy 16 mice.

1 reference

12 December 2020

Degeneration of beta-amyloid-associated cholinergic structures in transgenic APP SW mice.

1 reference

12 December 2020

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

1 reference

12 December 2020

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

1 reference

12 December 2020

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

12 December 2020

Selective loss of central cholinergic neurons in Alzheimer's disease

1 reference

12 December 2020

Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss

1 reference

12 December 2020

Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes

1 reference

12 December 2020

A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome

1 reference

12 December 2020

192 immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells

1 reference

12 December 2020

Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue

1 reference

12 December 2020

Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease

1 reference

12 December 2020

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

1 reference

12 December 2020

1 reference

12 December 2020

Down's syndrome individuals begin life with normal levels of brain cholinergic markers

1 reference

12 December 2020

Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease

1 reference

12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

12 December 2020

Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue

1 reference

12 December 2020

Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.

1 reference

12 December 2020

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

1 reference

12 December 2020

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

1 reference

12 December 2020

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

1 reference

12 December 2020

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

12 December 2020

On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis

1 reference

12 December 2020

Genetically engineered mouse models of neurodegenerative diseases

1 reference

12 December 2020

Challenging assumptions about Alzheimer's disease: mild cognitive impairment and the cholinergic hypothesis.

1 reference

12 December 2020

Nicotinic receptors in aging and dementia

1 reference

12 December 2020

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

1 reference

12 December 2020

Cholinergic neuropathology in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.

1 reference

12 December 2020

The cholinergic hypothesis of geriatric memory dysfunction

1 reference

12 December 2020

Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory

1 reference

12 December 2020

Cerebral cortical astroglia from the trisomy 16 mouse, a model for down syndrome, produce neuronal cholinergic deficits in cell culture

1 reference

12 December 2020

Cell lines derived from hippocampal neurons of the normal and trisomy 16 mouse fetus (a model for Down syndrome) exhibit neuronal markers, cholinergic function, and functional neurotransmitter receptors

1 reference

12 December 2020

Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease

1 reference

12 December 2020

The synaptic Abeta hypothesis of Alzheimer disease

1 reference

12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

12 December 2020

Single and multiple transgenic mice as models for Alzheimer's disease

1 reference

12 December 2020

Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes

1 reference

12 December 2020

The cholinergic system in Down's syndrome.

1 reference

12 December 2020

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

1 reference

12 December 2020

Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

1 reference

12 December 2020

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

12 December 2020

Regional alteration of cholinergic function in central neurons of trisomy 16 mouse fetuses, an animal model of human trisomy 21 (Down syndrome)

1 reference

12 December 2020

Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype

1 reference

12 December 2020

Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.

1 reference

12 December 2020

A rapid radiochemical method for the determination of choline acetyltransferase

1 reference

12 December 2020

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1 reference

12 December 2020

Impaired cholinergic function in cell lines derived from the cerebral cortex of normal and trisomy 16 mice

1 reference

12 December 2020

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

1 reference

12 December 2020

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment

1 reference

12 December 2020

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1 reference

12 December 2020

Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.

1 reference

12 December 2020

Down syndrome phenotypes: the consequences of chromosomal imbalance

1 reference

12 December 2020

Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase

1 reference

12 December 2020

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

12 December 2020

Multiple central nervous system targets for eliciting beneficial effects on memory and cognition.

1 reference

12 December 2020

The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development

1 reference

12 December 2020

Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome

1 reference

12 December 2020

beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons

1 reference

12 December 2020

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

12 December 2020

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

12 December 2020

Cholinergic markers in elderly patients with early signs of Alzheimer disease

1 reference

12 December 2020

Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies

1 reference

12 December 2020

Analysis of cholinergic markers, biogenic amines, and amino acids in the CNS of two APP overexpression mouse models

1 reference

12 December 2020

Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons

1 reference

12 December 2020

Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Production of specific antisera and monoclonal antibodies to choline acetyltransferase: characterization and use for identification of cholinergic neurons

1 reference

12 December 2020

Down syndrome, Alzheimer's disease and the trisomy 16 mouse

1 reference

12 December 2020

Neuron loss in APP transgenic mice

1 reference

12 December 2020

Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice

1 reference

12 December 2020

Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice

1 reference

12 December 2020

Mild cognitive impairment and the cholinergic hypothesis: a very different take on recent data

1 reference

12 December 2020

Intracellular and extracellular Abeta, a tale of two neuropathologies

1 reference

12 December 2020

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

1 reference

12 December 2020

Abnormalities of the nucleus basalis in Down's syndrome

1 reference

12 December 2020

Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases

1 reference

12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

12 December 2020

Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons

1 reference

12 December 2020

Immunolesion by 192IgG-saporin of rat basal forebrain cholinergic system: a useful tool to produce cortical cholinergic dysfunction

1 reference

12 December 2020

Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice.

1 reference

12 December 2020

Differential cholinergic regulation in Alzheimer's patients compared to controls following chronic blockade with scopolamine: a SPECT study.

1 reference

12 December 2020

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

12 December 2020

Cholinergic systems in the rat brain: I. projections to the limbic telencephalon

1 reference

12 December 2020

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

12 December 2020

Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes

1 reference

12 December 2020

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

1 reference

12 December 2020

Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human beta-amyloid precursor protein

1 reference

12 December 2020

10.1007/S11064-007-9497-4

Identifiers

DOI

1 reference

17 August 2017

1 reference