(Q37078957)

18 August 2017

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title

The emerging role of anti-angiogenic therapy for malignant glioma (English)

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18 August 2017

angiogenesis inhibitor

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2

Annick Desjardins

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18 August 2017

1

David A Reardon

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18 August 2017

3

Jeremy N Rich

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18 August 2017

James J Vredenburgh

4

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18 August 2017

7 February 2008

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Current Treatment Options in Oncology

18 August 2017

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18 August 2017

9

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18 August 2017

1

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18 August 2017

1-22

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https://scigraph.springernature.com/pub.10.1007/s11864-008-0052-6

18 August 2017

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cites work

Tumor angiogenesis: therapeutic implications

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PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinase activity in combination with radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Effect of bevacizumab on radiation necrosis of the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Involvement of the multidrug resistance protein 3 in drug sensitivity and its expression in human glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Angiogenesis in gliomas: biology and molecular pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Proteases and glioma angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

The role of the extracellular matrix in angiogenesis in malignant glioma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Tumor angiogenesis of low-grade astrocytomas measured by dynamic susceptibility contrast-enhanced MRI (DSC-MRI) is predictive of local tumor control after radiation therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Vascular morphology and angiogenesis in glial tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11864-008-0052-6

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

21 January 2018

1 reference

12 December 2020

Expression of VEGFR3 in glioma endothelium correlates with tumor grade.

1 reference

12 December 2020

Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents.

1 reference

12 December 2020

Lessons from phase III clinical trials on anti-VEGF therapy for cancer

1 reference

12 December 2020

Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer

1 reference

12 December 2020

Leukocytes and platelets of patients with cancer contain high levels of vascular endothelial growth factor

1 reference

12 December 2020

Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours.

1 reference

12 December 2020

Patterns of cyclooxygenase-1 and -2 expression in human gliomas in vivo.

1 reference

12 December 2020

Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas.

1 reference

12 December 2020

UKT-04 trial of continuous metronomic low-dose chemotherapy with methotrexate and cyclophosphamide for recurrent glioblastoma.

1 reference

12 December 2020

Antiangiogenic therapy against experimental glioblastoma using genetically engineered cells producing interferon-alpha, angiostatin, or endostatin

1 reference

12 December 2020

Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy

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12 December 2020

Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis

1 reference

12 December 2020

MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors.

1 reference

12 December 2020

Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme.

1 reference

12 December 2020

Invasion as limitation to anti-angiogenic glioma therapy

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12 December 2020

Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma

1 reference

12 December 2020

The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis

1 reference

12 December 2020

PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization

1 reference

12 December 2020

VEGF-Trap: a VEGF blocker with potent antitumor effects

1 reference

12 December 2020

Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging.

1 reference

12 December 2020

Vessel tortuosity and brain tumor malignancy: a blinded study

1 reference

12 December 2020

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

1 reference

12 December 2020

Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas.

1 reference

12 December 2020

Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors.

1 reference

12 December 2020

Genetic and hypoxic regulation of angiogenesis in gliomas

1 reference

12 December 2020

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

12 December 2020

Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme

1 reference

12 December 2020

Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2.

1 reference

12 December 2020

Model selection in magnetic resonance imaging measurements of vascular permeability: Gadomer in a 9L model of rat cerebral tumor.

1 reference

12 December 2020

Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice

1 reference

12 December 2020

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

1 reference

12 December 2020

Integrins: molecular targets in cancer therapy

1 reference

12 December 2020

Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas

1 reference

12 December 2020

Dynamic susceptibility contrast-enhanced echo-planar imaging of cerebral gliomas. Effect of contrast medium extravasation.

1 reference

12 December 2020

Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker

1 reference

12 December 2020

Imaging angiogenesis: applications and potential for drug development

1 reference

12 December 2020

A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.

1 reference

12 December 2020

The antiproliferative effect of interferon and the mitogenic activity of growth factors are independent cell cycle events. Studies with vascular smooth muscle cells and endothelial cells

1 reference

12 December 2020

Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway

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12 December 2020

Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

1 reference

12 December 2020

Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches.

1 reference

12 December 2020

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

1 reference

12 December 2020

Characterization of angiogenesis and microcirculation of high-grade glioma: an intravital multifluorescence microscopic approach in the athymic nude mouse.

1 reference

12 December 2020

Multidrug resistance in brain tumors: roles of the blood-brain barrier

1 reference

12 December 2020

Angiogenesis in malignant gliomas

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12 December 2020

Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor

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12 December 2020

Isolation of putative progenitor endothelial cells for angiogenesis

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12 December 2020

The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice.

1 reference

12 December 2020

Chemotherapy delivery issues in central nervous system malignancy: a reality check.

1 reference

12 December 2020

Immunohistochemical localization of basic fibroblast growth factor in astrocytomas.

1 reference

12 December 2020

ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors

1 reference

12 December 2020

1 reference

12 December 2020

Phase II trial with BCNU plus alpha-interferon in patients with recurrent high-grade gliomas.

1 reference

12 December 2020

Thalidomide is an inhibitor of angiogenesis

1 reference

12 December 2020

Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue.

1 reference

12 December 2020

Predicting benefit from anti-angiogenic agents in malignancy

1 reference

12 December 2020

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

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12 December 2020

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

1 reference

12 December 2020

Antiangiogenic strategies on defense: on the possibility of blocking rebounds by the tumor vasculature after chemotherapy

1 reference

12 December 2020

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

1 reference

12 December 2020

Response criteria for phase II studies of supratentorial malignant glioma

1 reference

12 December 2020

Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials

1 reference

12 December 2020

Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets

1 reference

12 December 2020

Insulin-like growth factor type I biology and targeting in malignant gliomas

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12 December 2020

Recurrent glioblastoma multiforme: advances in treatment and promising drug candidates

1 reference

12 December 2020

Acidic and basic fibroblast growth factors are present in glioblastoma multiforme

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12 December 2020

Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo.

1 reference

12 December 2020

Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity

1 reference

12 December 2020

A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer

1 reference

12 December 2020

1 reference

12 December 2020

Platelet: transporter of vascular endothelial growth factor

1 reference

12 December 2020

alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin.

1 reference

12 December 2020

18F-FDOPA PET imaging of brain tumors: comparison study with 18F-FDG PET and evaluation of diagnostic accuracy

1 reference

12 December 2020

Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme

1 reference

12 December 2020

Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours

1 reference

12 December 2020

Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma

1 reference

12 December 2020

Vascular endothelial growth factor signaling pathways: therapeutic perspective

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12 December 2020

Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group

1 reference

12 December 2020

Comparison of microvascular permeability measurements, K(trans), determined with conventional steady-state T1-weighted and first-pass T2*-weighted MR imaging methods in gliomas and meningiomas.

1 reference

12 December 2020

Irinotecan therapy in adults with recurrent or progressive malignant glioma.

1 reference

12 December 2020

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

1 reference

12 December 2020

Autocrine platelet-derived growth factor-dependent gene expression in glioblastoma cells is mediated largely by activation of the transcription factor sterol regulatory element binding protein and is associated with altered genotype and patient surv

1 reference

12 December 2020

A phase I trial of a new recombinant human beta-interferon (BG9015) for the treatment of patients with recurrent gliomas.

1 reference

12 December 2020

The biology of VEGF and its receptors

1 reference

12 December 2020

1 reference

12 December 2020

Phase I clinical and pharmacokinetic study of irinotecan in adults with recurrent malignant glioma

1 reference

12 December 2020

Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors

1 reference

12 December 2020

Salvage chemotherapy with CPT-11 for recurrent glioblastoma multiforme

1 reference

12 December 2020

Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery.

1 reference

12 December 2020

Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?

1 reference

12 December 2020

Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells

1 reference

12 December 2020

Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study

1 reference

12 December 2020

Cancer stem cells in nervous system tumors

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12 December 2020

PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

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12 December 2020

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

1 reference

12 December 2020

Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab

1 reference

12 December 2020

Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen

1 reference

12 December 2020

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

1 reference

12 December 2020

Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer

1 reference

12 December 2020

SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models

1 reference

12 December 2020

A perivascular niche for brain tumor stem cells

1 reference

12 December 2020

Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma.

1 reference

12 December 2020

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.

1 reference

12 December 2020

Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells

1 reference

12 December 2020

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1 reference

12 December 2020

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.

1 reference

12 December 2020

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

1 reference

12 December 2020

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

12 December 2020

Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis

1 reference

12 December 2020

Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

1 reference

12 December 2020

Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model

1 reference

12 December 2020

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

1 reference

12 December 2020

Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation

1 reference

12 December 2020

Identification of a cancer stem cell in human brain tumors

1 reference

12 December 2020

MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy.

1 reference

12 December 2020

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy

1 reference

12 December 2020

Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy.

1 reference

12 December 2020

Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma

1 reference

12 December 2020

Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials

1 reference

12 December 2020

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

12 December 2020

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients

1 reference

12 December 2020

Reversible posterior leukoencephalopathy syndrome and bevacizumab.

1 reference

12 December 2020

Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

1 reference

12 December 2020

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1 reference

12 December 2020

Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.

1 reference

12 December 2020

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

1 reference

12 December 2020

Integrins and angiogenesis: a sticky business

1 reference

12 December 2020

Blood-brain barrier drug targeting: the future of brain drug development

1 reference

12 December 2020

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis.

1 reference

12 December 2020

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

1 reference

12 December 2020

A review of micro- and macrovascular analyses in the assessment of tumor-associated vasculature as visualized by MR.

1 reference

12 December 2020

A cyclooxygenase-2 (COX-2) inhibitor compared with dexamethasone in a survival study of rats with intracerebral 9L gliosarcomas

1 reference

12 December 2020

Mechanisms of angiogenesis in gliomas

1 reference

12 December 2020

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

1 reference

12 December 2020

Angiostatin suppresses malignant glioma growth in vivo.

1 reference

12 December 2020

Quantification of blood flow in brain tumors: comparison of arterial spin labeling and dynamic susceptibility-weighted contrast-enhanced MR imaging

1 reference

12 December 2020

Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows.

1 reference

12 December 2020

Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG.

1 reference

12 December 2020

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

1 reference

12 December 2020

Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts.

1 reference

12 December 2020

Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma.

1 reference

12 December 2020

Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis

1 reference

12 December 2020

Microvessel density is a prognostic indicator for patients with astroglial brain tumors.

1 reference

12 December 2020

Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4.

1 reference

12 December 2020

The multidrug-resistance gene MDR1 is expressed in human glial tumors

1 reference

12 December 2020

Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy

1 reference

12 December 2020

Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.

1 reference

12 December 2020

Hypoxia inducible factor-1 independent pathways in tumor angiogenesis.

1 reference

12 December 2020

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

1 reference

12 December 2020

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse

1 reference

12 December 2020

Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms

1 reference

12 December 2020

Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption

1 reference

12 December 2020

Invasive behaviour of human gliomas is mediated by interindividually different integrin patterns.

1 reference

12 December 2020

Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins αvβ3 and αvβ5 in patients with advanced solid tumours

1 reference

12 December 2020

Suppression of malignant glioma recurrence in a newly developed animal model by endogenous inhibitors.

1 reference

12 December 2020

Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2.

1 reference

12 December 2020

In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor.

1 reference

12 December 2020

Magnetic resonance angiography visualization of abnormal tumor vasculature in genetically engineered mice

1 reference

12 December 2020

Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma.

1 reference

12 December 2020

Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme

1 reference

12 December 2020

The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency

1 reference

12 December 2020

Antiangiogenic therapy: a universal chemosensitization strategy for cancer?

1 reference

12 December 2020

Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors.

1 reference

12 December 2020

Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

1 reference

12 December 2020

Angiogenic factors in the central nervous system

1 reference

12 December 2020

Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma

1 reference

12 December 2020

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

1 reference

12 December 2020

The anti-angiogenic basis of metronomic chemotherapy

1 reference

12 December 2020

Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas

1 reference

12 December 2020

Integrin signalling during tumour progression

1 reference

12 December 2020

Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

1 reference

12 December 2020

IS20I, a specific alphavbeta3 integrin inhibitor, reduces glioma growth in vivo.

1 reference

12 December 2020

Preuss Resident Research Award: bone marrow-derived Flk-1-expressing CD34+ cells contribute to the endothelium of tumor vessels in mouse brain.

1 reference

12 December 2020

The blood-brain barrier and oncology: new insights into function and modulation

1 reference

12 December 2020

Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities

1 reference

12 December 2020

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

12 December 2020

Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: a complementation antiangiogenic strategy.

1 reference

12 December 2020

Suppression of glioblastoma cell growth following antisense oligonucleotide-mediated inhibition of fibroblast growth factor receptor expression

1 reference

12 December 2020

Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

1 reference

12 December 2020

Modelling of the blood-brain barrier in drug discovery and development.

1 reference

12 December 2020

Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.

1 reference

12 December 2020

Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition

1 reference

12 December 2020

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells

1 reference

12 December 2020

Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11.

1 reference

12 December 2020

Ultrastructure of capillary walls in human brain tumors

1 reference

12 December 2020

The multifaceted circulating endothelial cell in cancer: towards marker and target identification.

1 reference

12 December 2020

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

12 December 2020

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

12 December 2020

Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.

1 reference

12 December 2020

Tumor angiogenesis: a quantitative method for histologic grading.

1 reference

12 December 2020

Thalidomide as an anti-angiogenic agent in relapsed gliomas

1 reference

12 December 2020

PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter.

1 reference

12 December 2020

Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy

1 reference

12 December 2020

Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study

1 reference

12 December 2020

10.1007/S11864-008-0052-6

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18256938