(Q37103690)

18 August 2017

1 reference

title

Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer (English)

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18 August 2017

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Laura C Kelley

1

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18 August 2017

Sohrab Shahab

series ordinal

2

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18 August 2017

Scott A Weed

series ordinal

3

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18 August 2017

publication date

7 March 2008

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Clinical & Experimental Metastasis

18 August 2017

published in

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18 August 2017

volume

25

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18 August 2017

issue

4

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18 August 2017

page(s)

289-304

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https://scigraph.springernature.com/pub.10.1007/s10585-008-9154-6

18 August 2017

exact match

0 references

cites work

Regulation of the actin cytoskeleton in cancer cell migration and invasion

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Amplification of the 3q26.3 locus is associated with progression to invasive cancer and is a negative prognostic factor in head and neck squamous cell carcinomas

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Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

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Autotaxin expression in non-small-cell lung cancer

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ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Genetic imbalances with impact on survival in head and neck cancer patients

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron

21 January 2018

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The RIN family of Ras effectors.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Cortactin: the gray eminence of the cytoskeleton

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-008-9154-6

Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities

21 January 2018

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12 December 2020

Functional dissection of human protease mu-calpain in cell migration using RNAi

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12 December 2020

Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

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12 December 2020

The great escape: when cancer cells hijack the genes for chemotaxis and motility

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12 December 2020

Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma.

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12 December 2020

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

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12 December 2020

Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules

1 reference

12 December 2020

Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells

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12 December 2020

Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition

1 reference

12 December 2020

Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease

1 reference

12 December 2020

Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number.

1 reference

12 December 2020

Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin

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12 December 2020

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

12 December 2020

Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck

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12 December 2020

Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis

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12 December 2020

Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology.

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12 December 2020

Unraveling the chromosomal aberrations of head and neck squamous cell carcinoma: a review

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12 December 2020

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

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12 December 2020

Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma

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12 December 2020

Cutting to the chase: calpain proteases in cell motility

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12 December 2020

A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth

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12 December 2020

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

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12 December 2020

Regulating cell migration: calpains make the cut.

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12 December 2020

Focal adhesion kinase: a potential target in cancer therapy

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12 December 2020

Cell migration in tumors

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12 December 2020

Overexpression of phospholipase D1 in human breast cancer tissues

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12 December 2020

A role for LIM kinase in cancer invasion.

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12 December 2020

Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma.

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12 December 2020

Phospholipase D couples survival and migration signals in stress response of human cancer cells

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12 December 2020

The biology of cell locomotion within three-dimensional extracellular matrix

1 reference

12 December 2020

Cofilin phosphatases and regulation of actin dynamics

1 reference

12 December 2020

Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase

1 reference

12 December 2020

p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate

1 reference

12 December 2020

Phospholipase D1 regulates cell migration in a lipase activity-independent manner.

1 reference

12 December 2020

The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton

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12 December 2020

PI3K/Akt signalling pathway and cancer.

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12 December 2020

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

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12 December 2020

Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B.

1 reference

12 December 2020

Pores in the wall: claudins constitute tight junction strands containing aqueous pores

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12 December 2020

Recurrent coamplification of cytoskeleton-associated genesEMS1 andSHANK2 withCCND1 in oral squamous cell carcinoma

1 reference

12 December 2020

Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells

1 reference

12 December 2020

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1 reference

12 December 2020

The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells

1 reference

12 December 2020

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

12 December 2020

Phospholipase D: a lipid centric review

1 reference

12 December 2020

Isoform specific function of calpain 2 in regulating membrane protrusion

1 reference

12 December 2020

Cellular motility driven by assembly and disassembly of actin filaments

1 reference

12 December 2020

The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue.

1 reference

12 December 2020

Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines

1 reference

12 December 2020

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

12 December 2020

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

1 reference

12 December 2020

The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly

1 reference

12 December 2020

Cortactin promotes cell motility by enhancing lamellipodial persistence

1 reference

12 December 2020

The involvement of the chromosome 11q13 region in human malignancies: Cyclin D1 and EMS1 are two new candidate oncogenes-a review

1 reference

12 December 2020

Expression profiling and prediction of distant metastases in head and neck squamous cell carcinoma

1 reference

12 December 2020

Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox

1 reference

12 December 2020

Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.

1 reference

12 December 2020

Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study

1 reference

12 December 2020

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

1 reference

12 December 2020

FAK regulates biological processes important for the pathogenesis of cancer

1 reference

12 December 2020

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

1 reference

12 December 2020

Autotaxin, tumor motility-stimulating exophosphodiesterase

1 reference

12 December 2020

p21-activated kinases in cancer

1 reference

12 December 2020

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

1 reference

12 December 2020

EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck

1 reference

12 December 2020

RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration

1 reference

12 December 2020

Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma.

1 reference

12 December 2020

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

1 reference

12 December 2020

Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells

1 reference

12 December 2020

Different expression patterns of calpain isozymes 1 and 2 (CAPN1 and 2) in squamous cell carcinomas (SCC) and basal cell carcinomas (BCC) of human skin

1 reference

12 December 2020

MIM, a potential metastasis suppressor gene in bladder cancer

1 reference

12 December 2020

Tumor cell invasion and survival in head and neck cancer

1 reference

12 December 2020

MIM: a multifunctional scaffold protein

1 reference

12 December 2020

Genetic differences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: construction of oncogenetic trees for tumor progression

1 reference

12 December 2020

Calpain mediates integrin-induced signaling at a point upstream of Rho family members

1 reference

12 December 2020

Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation

1 reference

12 December 2020

Phosphatidylinositol 3-kinases in tumor progression

1 reference

12 December 2020

Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation

1 reference

12 December 2020

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

1 reference

12 December 2020

Fra-1 a target for cancer prevention or intervention

1 reference

12 December 2020

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

1 reference

12 December 2020

Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin

1 reference

12 December 2020

Association of PI-3 kinase with PAK1 leads to actin phosphorylation and cytoskeletal reorganization

1 reference

12 December 2020

Molecular mediators of metastasis in head and neck squamous cell carcinoma

1 reference

12 December 2020

A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification

1 reference

12 December 2020

Specific Requirement for the p85-p110α Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells

1 reference

12 December 2020

Molecular profiling of tumor progression in head and neck cancer

1 reference

12 December 2020

Tumor invasion: role of growth factor-induced cell motility

1 reference

12 December 2020

Coronins: the return of the crown

1 reference

12 December 2020

Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas

1 reference

12 December 2020

Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene.

1 reference

12 December 2020

Intracellular signaling by phospholipase D as a therapeutic target

1 reference

12 December 2020

Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling

1 reference

12 December 2020

ARF proteins: roles in membrane traffic and beyond

1 reference

12 December 2020

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

12 December 2020

Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge

1 reference

12 December 2020

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

12 December 2020

Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization

1 reference

12 December 2020

Cortactin Overexpression Regulates Actin-Related Protein 2/3 Complex Activity, Motility, and Invasion in Carcinomas with Chromosome 11q13 Amplification

1 reference

12 December 2020

Tyrosine phosphorylation of missing in metastasis protein is implicated in platelet-derived growth factor-mediated cell shape changes

1 reference

12 December 2020

Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis

1 reference

12 December 2020

Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli

1 reference

12 December 2020

The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation

1 reference

12 December 2020

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

1 reference

12 December 2020

Phosphorylation of cortactin by p21-activated kinase.

1 reference

12 December 2020

Dynamin participates in focal extracellular matrix degradation by invasive cells

1 reference

12 December 2020

The claudin gene family: expression in normal and neoplastic tissues

1 reference

12 December 2020

Regulation of cancer cell motility through actin reorganization

1 reference

12 December 2020

Mechanisms of cancer cell invasion

1 reference

12 December 2020

Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities

1 reference

12 December 2020

Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression

1 reference

12 December 2020

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

1 reference

12 December 2020

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

1 reference

12 December 2020

Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor

1 reference

12 December 2020

Shank2 associates with and regulates Na+/H+ exchanger 3

1 reference

12 December 2020

Cortactin potentiates bone metastasis of breast cancer cells.

1 reference

12 December 2020

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

1 reference

12 December 2020

Claudin proteins in human cancer: promising new targets for diagnosis and therapy

1 reference

12 December 2020

ArfGAP family proteins in cell adhesion, migration and tumor invasion.

1 reference

12 December 2020

Multiple connections link FAK to cell motility and invasion

1 reference

12 December 2020

Differential regulation of cell motility and invasion by FAK

1 reference

12 December 2020

Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active

1 reference

12 December 2020

Cofilin promotes actin polymerization and defines the direction of cell motility

1 reference

12 December 2020

Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer

1 reference

12 December 2020

Advances in Rho-dependent actin regulation and oncogenic transformation

1 reference

12 December 2020

One ring to bind them. Septins and actin assembly

1 reference

12 December 2020

FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells.

1 reference

12 December 2020

Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins

1 reference

12 December 2020

Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway

1 reference

12 December 2020

Cellular characterization of a novel focal adhesion kinase inhibitor

1 reference

12 December 2020

Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma

1 reference

12 December 2020

Protein kinase C isoform expression in ovarian carcinoma correlates with indicators of poor prognosis

1 reference

12 December 2020

ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

1 reference

12 December 2020

Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells

1 reference

12 December 2020

Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits

1 reference

12 December 2020

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

1 reference

12 December 2020

Transmodulation between Phospholipase D and c-Src Enhances Cell Proliferation

1 reference

12 December 2020

Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification

1 reference

12 December 2020

Cortactin: coupling membrane dynamics to cortical actin assembly

1 reference

12 December 2020

Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.

1 reference

12 December 2020

Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein

1 reference

12 December 2020

Protein kinase C isoenzymes: regulation and function.

1 reference

12 December 2020

Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase

1 reference

12 December 2020

A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes

1 reference

12 December 2020

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

1 reference

12 December 2020

Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

1 reference

12 December 2020

DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma

1 reference

12 December 2020

Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration

1 reference

12 December 2020

Integrin signalling during tumour progression

1 reference

12 December 2020

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

12 December 2020

Cell migration: integrating signals from front to back

1 reference

12 December 2020

A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation

1 reference

12 December 2020

Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function

1 reference

12 December 2020

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

12 December 2020

Calpain-mediated proteolysis of talin regulates adhesion dynamics

1 reference

12 December 2020

Gene ontology: tool for the unification of biology

1 reference

12 December 2020

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

1 reference

12 December 2020

DNA copy number gains in head and neck squamous cell carcinoma.

1 reference

12 December 2020

Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains

1 reference

12 December 2020

Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently

1 reference

12 December 2020

Overexpression of Fos-related antigen-1 in head and neck squamous cell carcinoma

1 reference

12 December 2020

Phosphoinositide 3-kinase signalling pathways

1 reference

12 December 2020

Borg proteins control septin organization and are negatively regulated by Cdc42

1 reference

12 December 2020

Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric site

1 reference

12 December 2020

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

1 reference

12 December 2020

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

1 reference

12 December 2020

10.1007/S10585-008-9154-6

Identifiers

DOI

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release_4ouda5siqvgb3alcqivx7jmmqq

18 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4ouda5siqvgb3alcqivx7jmmqq

24 November 2022

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