(Q37255013)

19 August 2017

1 reference

title

Novel therapeutic modalities to address nondrugable protein interaction targets (English)

1 reference

19 August 2017

Errol B De Souza

1

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19 August 2017

Sharon T Cload

series ordinal

2

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19 August 2017

Patrick Shannon Pendergrast

series ordinal

3

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19 August 2017

Dinah W Y Sah

series ordinal

4

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19 August 2017

language of work or name

English

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publication date

27 August 2008

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19 August 2017

published in

Neuropsychopharmacology

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19 August 2017

volume

34

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19 August 2017

issue

1

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19 August 2017

page(s)

142-158

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https://scigraph.springernature.com/pub.10.1038/npp.2008.115

19 August 2017

exact match

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cites work

Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

Oligonucleotide inhibitors of P-selectin-dependent neutrophil-platelet adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

Anti-L-selectin aptamers: binding characteristics, pharmacokinetic parameters, and activity against an intravascular target in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Antigen-independent selection of intracellular stable antibody frameworks

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Fusion antibody for Alzheimer's disease with bidirectional transport across the blood-brain barrier and abeta fibril disaggregation

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

RNAi therapeutics: a potential new class of pharmaceutical drugs

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

2'-Deoxy purine, 2'-O-methyl pyrimidine (dRmY) aptamers as candidate therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Inhibition of complement activation by pexelizumab reduces death in patients undergoing combined aortic valve replacement and coronary artery bypass surgery

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Co-expression of anti-NFkappaB RNA aptamers and siRNAs leads to maximal suppression of NFkappaB activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Pegaptanib: a novel approach to ocular neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Chemical modification of siRNAs to improve serum stability without loss of efficacy.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

https://api.crossref.org/works/10.1038%2FNPP.2008.115

1 reference

7 January 2021

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Formulation and delivery issues for monoclonal antibody therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

siRNA relieves chronic neuropathic pain

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Post-SELEX combinatorial optimization of aptamers

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Antibody engineering and modification technologies

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Multiple actions of systemic artemin in experimental neuropathy

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Diversity of oligonucleotide functions

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Pharmacokinetics and biodistribution of novel aptamer compositions

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Engineered antibody fragments and the rise of single domains

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Potent 2'-amino-2'-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A single siRNA suppresses fatal encephalitis induced by two different flaviviruses

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Transvascular delivery of small interfering RNA to the central nervous system.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Peripheral and Central Mechanisms of NGF-induced Hyperalgesia

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Modulation of survival motor neuron pre-mRNA splicing by inhibition of alternative 3' splice site pairing

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Modified RNA sequence pools for in vitro selection

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Intracellular antibodies (intrabodies) and their therapeutic potential

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Human antibodies from transgenic animals

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Correction of SMN2 Pre-mRNA splicing by antisense U7 small nuclear RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Anti-interleukin-12 antibody for active Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Understanding the IL-23-IL-17 immune pathway

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Combinational approach of intrabody with enhanced Hsp70 expression addresses multiple pathologies in a fly model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

GFRalpha3 is expressed predominantly in nociceptive sensory neurons

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Potent 2'-amino-, and 2'-fluoro-2'-deoxyribonucleotide RNA inhibitors of keratinocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Transgenic mice in drug dependence research.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792-associated meningoencephalitis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

The generation and characterization of antagonist RNA aptamers to human oncostatin M

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

The generation and characterisation of antagonist RNA aptamers to MCP-1

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

RNA aptamers as reversible antagonists of coagulation factor IXa.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

RNA aptamers as pathway-specific MAP kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Non-CpG-containing antisense 2'-methoxyethyl oligonucleotides activate a proinflammatory response independent of Toll-like receptor 9 or myeloid differentiation factor 88.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Complex target SELEX.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Unilateral intraputaminal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year each of treatment and withdrawal

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Antisense oligonucleotide therapy for neurodegenerative disease.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Targeted delivery of proteins across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Preclinical assessment of therapeutic antibodies against human CD40 and human interleukin-12/23p40 in a nonhuman primate model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Latest technologies for the enhancement of antibody affinity

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Building oligonucleotide therapeutics using non-natural chemistries

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Progress in thioaptamer development

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Distribution of GDNF family receptor alpha3 and RET in rat and human non-neural tissues

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Selection of RNA aptamers to the Alzheimer's disease amyloid peptide

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.115

7 January 2021

Identifiers

DOI

10.1038/NPP.2008.115

1 reference

19 August 2017

1 reference