(Q37598928)

21 August 2017

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title

Strategies for short hairpin RNA delivery in cancer gene therapy (English)

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21 August 2017

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Shou-Li Wang

1

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21 August 2017

Hui-Hua Yao

series ordinal

2

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21 August 2017

Zheng-Hong Qin

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 November 2009

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Expert Opinion on Biological Therapy

21 August 2017

published in

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21 August 2017

volume

9

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21 August 2017

issue

11

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21 August 2017

page(s)

1357-1368

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Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference.

21 August 2017

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21 January 2018

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Blocking mouse MMP-9 production in tumor cells and mouse cornea by short hairpin (sh) RNA encoding plasmids

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Cloned zebrafish by nuclear transfer from long-term-cultured cells

21 January 2018

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Effective expression of small interfering RNA in human cells

21 January 2018

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Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

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21 January 2018

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Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

21 January 2018

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

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Strategies for generation of an siRNA expression library directed against the human genome.

21 January 2018

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Synthetic shRNAs as potent RNAi triggers.

21 January 2018

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Progress towards in vivo use of siRNAs

21 January 2018

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21 January 2018

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Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

21 January 2018

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siRNA and the lung: research tool or therapeutic drug?

21 January 2018

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Nonviral vectors in the new millennium: delivery barriers in gene transfer

21 January 2018

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Delivery of RNA interference

21 January 2018

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Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors

21 January 2018

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Potential applications of RNA interference technology in the treatment of cancer

21 January 2018

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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

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A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

21 January 2018

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Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic

21 January 2018

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Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach

21 January 2018

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Tissue-selective RNA interference in prostate cancer cell using prostate specific membrane antigen promoter/enhancer

21 January 2018

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A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.

21 January 2018

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Defining the optimal parameters for hairpin-based knockdown constructs

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712590903236843

Expression strategies for short hairpin RNA interference triggers

21 January 2018

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Optimization and characterization of tRNA-shRNA expression constructs

21 January 2018

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Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown

21 January 2018

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A tightly regulated Pol III promoter for synthesis of miRNA genes in tandem

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712590903236843

Promoter choice affects the potency of HIV-1 specific RNA interference

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712590903236843

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

21 January 2018

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21 January 2018

RNA interference in mice

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Applications of lentiviral vectors for shRNA delivery and transgenesis

21 January 2018

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Adeno-associated virus vectors for short hairpin RNA expression

21 January 2018

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VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth.

21 January 2018

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Inhibition of renal cancer cell growth by oncolytic adenovirus armed short hairpin RNA targeting hTERT gene

21 January 2018

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Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway

21 January 2018

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Inhibition of cervical cancer cell growth by human papillomavirus virus-like particles packaged with human papillomavirus oncoprotein short hairpin RNAs.

21 January 2018

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E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells

21 January 2018

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Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.

21 January 2018

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AAV vector integration sites in mouse hepatocellular carcinoma.

21 January 2018

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A combinatorial polymer library approach yields insight into nonviral gene delivery

21 January 2018

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Nonviral gene delivery: what we know and what is next

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712590903236843

Synthetic vs. natural/biodegradable polymers for delivery of shRNA-based cancer therapies

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712590903236843

Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Optimization of nuclear localization signal for nuclear transport of DNA-encapsulating particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Nanoparticles for drug delivery in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Extracellular matrix glycoproteins and diffusion barriers in human astrocytic tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Factors affecting the clearance and biodistribution of polymeric nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Lentivirus-mediated gene therapy by suppressing survivin in BALB/c nude mice bearing oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

EphB4 expression and biological significance in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

An inducible short-hairpin RNA vector against osteopontin reduces metastatic potential of human esophageal squamous cell carcinoma in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Cationic lipids and polymers mediated vectors for delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Lipid-based systemic delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

shRNA and siRNA delivery to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Can nuclear localization signals enhance nuclear localization of plasmid DNA?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Intravenous, non-viral RNAi gene therapy of brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Targeted nucleic acid delivery into tumors: new avenues for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Selective gene delivery for cancer therapy using cationic liposomes: in vivo proof of applicability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Development and characterisation of chitosan nanoparticles for siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Selection of optimal sites for TGFB1 gene silencing by chitosan-TPP nanoparticle-mediated delivery of shRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

The nuclear pore complex: the gateway to successful nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Enhanced nuclear import and transfection efficiency of plasmid DNA using streptavidin-fused importin-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Targeting hypoxia-inducible factor-1alpha with Tf-PEI-shRNA complex via transferrin receptor-mediated endocytosis inhibits melanoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Bacterial delivery of siRNAs: a new approach to solid tumor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Retroviral insertional mutagenesis: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712590903236843

10.1517/14712590903236843

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference